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Camizestrant reduced the risk of disease progression or death by 56% in patients with advanced HR-positive breast cancer with an emergent ESR1 tumor mutation in SERENA-6 Phase III trial
01 Jun 2025 12:10 GMT
… inhibitor (AI) (anastrozole or letrozole) in … Notes
HR-positive breast cancer
Breast cancer is the second … Estrogen receptor positive breast cancers have patient specific … metastatic hormone receptor‑positive breast cancer. Breast Cancer Res. 2021; 23 …
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Early Switch With Camizestrant Plus Continued CDK4/6 Inhibition Nearly Doubles PFS in ESR1-Mutant, ER+/HER2– Advanced Breast Cancer
01 Jun 2025 13:07 GMT
… advanced hormone receptor–positive breast cancer. Although rare at diagnosis … or continued AI with anastrozole or letrozole plus CDK4 … , HER2-negative advanced breast cancer is critical, because … , HER2-negative metastatic breast cancer in patients with ESR1 …
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Breakthrough Cancer test allows more Breast Cancer patients to skip Chemotherapy
25 May 2025 15:50 GMT
… decades, the diagnosis of breast cancer meant enduring the nightmare of … activity of 70 genes within breast cancer. The test, now confirmed … the form of tamoxifen or anastrozole, which are pills to … .
For women diagnosed with breast cancer, this advance is a …
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Neoadjuvant Letrozole/Entrectinib Shows Limited Activity in Invasive Lobular Breast Cancer
16 May 2025 22:45 GMT
… breast cancer comprises approximately 15% of all breast cancer … of invasive lobular breast tumors lack E-cadherin. … , HER2-negative breast cancer who underwent surgery … anastrozole in neoMONARCH, phase II neoadjuvant study in HR+/HER2- breast cancer …
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Naples Prognostic Score (NPS) as a Novel Prognostic Score for Stage III Breast Cancer Patients: A Real-World Retrospective Study
12 May 2025 12:12 GMT
… endocrine therapy (tamoxifen, anastrozole, letrozole), and targeted therapy … of Stage III Breast Cancer Patients
This … III breast cancer. Eventually, 306 stage III breast cancer patients … breast cancer: a systematic review and meta-analysis. Breast Cancer …
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Considerations for the Use of Abemaciclib vs Ribociclib in Breast Cancer
09 May 2025 17:50 GMT
… ;6 inhibitors to prevent breast cancer reoccurrence after treatment.2
The … mg per day or anastrozole 1 mg per day … inhibitors in patients with early breast cancer. Ther Adv Med Oncol … node-positive, high-risk, early breast cancer (monarchE). J Clin Oncol. 2020 …
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IBTR Rates With Margin Widths Not Clinically Meaningful in Breast Cancer
02 May 2025 20:46 GMT
… , regarding rates of ipsilateral breast tumor recurrence (IBTR), according to … and 0.4%; contralateral breast cancer in 2.6%, 3. … similar between the tamoxifen and anastrozole arms, and there were … width on IBTR and all breast cancer events,” Wapnir said.
Of …
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Trends in Combinatorial Endocrine Therapy for Breast Cancer Across Six Cities in China(2016-2021)
02 May 2025 08:42 GMT
… expression profiles, breast cancers are classified into … breast cancer (TNBC).4 ER positive breast cancer represents approximately 70% of all breast cancer … toremifene; AIs encompass anastrozole, letrozole, and … of prescriptions for breast cancer patients. The …
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What to know about estrogen inhibitors for breast cancer
29 Apr 2025 09:53 GMT
… and surgery.
HR-positive breast cancers require estrogen to grow. … breast cancer. Research suggests that exemestane and anastrozole may reduce the risk of breast cancer … at treating ER-positive breast cancer.
HR-positive breast cancers tend to grow …
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Keeping Up With The Growing Number of Treatments for Breast Cancer
22 Apr 2025 18:19 GMT
… of early detection.³,⁵
Breast cancer treatment is highly … women or aromatase inhibitors (anastrozole, letrozole, exemestane) … patients receiving trastuzumab.
Breast cancer remains a critical … positioned to support breast cancer patients through our …
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