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Basilea awarded BARDA contract for the development of novel oral phase 3─ready antibiotic ceftibuten─ledaborbactam
27 Sep 2025 08:44 GMT
… respectively) as well as multidrug-resistant (MDR) Enterobacterales. Ceftibuten-ledaborbactam … and community settings.
Increasing resistance of bacteria causing complicated … limited availability of effective oral antibiotic treatment options. Currently, there …
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Identifying Key Genes for Vancomycin-Resistant Enterococcus
27 Sep 2025 08:38 GMT
… complex genetic mechanisms that underlie antibiotic resistance. By unraveling these intricate … tract infections, antibiotic resistance, public health, genetic resistance mechanisms.
Tags: antibiotic resistance in Enterococcusclinical microbiology …
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Romanian hospital under investigation after six child deaths linked to antibiotic-resistant bacteria
26 Sep 2025 14:56 GMT
… Romania, while affected by an antibiotic-resistant bacteria.
Nine babies at the …
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Integration of susceptibility testing and local surveillance to inform antibiotic use
26 Sep 2025 23:03 GMT
Panelists discuss the challenges of implementing susceptibility testing for new antibiotics, emphasizing the need for close lab-clinician collaboration, streamlined reflex testing protocols, and investment in diagnostic infrastructure to ensure timely and …
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Evidence and trials informing treatment of resistant Gram-negative infections
26 Sep 2025 23:03 GMT
… novel antibiotic combinations targeting metallo-β-lactamase (MBL)–producing and other multidrug-resistant … clinical trials, the complexity of resistance mechanisms, and the potential for …
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Strategies for addressing MBL infections with targeted antibiotic combination therapy, and clinical insights from the REVISIT study
26 Sep 2025 23:03 GMT
Panelists discuss the innovative use of the aztreonam-avibactam combination to combat complex β-lactamase–mediated resistance, highlighting promising laboratory data, challenges in clinical trial enrollment for resistant infections, and the ongoing need …
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Parental Antibiotic Self-Medication Awareness in Bandung
26 Sep 2025 22:19 GMT
… interventions.
The landscape of antibiotic resistance is evolving rapidly, with … be crucial in combating antibiotic resistance and safeguarding future generations … ;s12887-025-06084-8
Keywords: Antibiotic resistance, self-medication, parental knowledge, …
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Basilea Secures BARDA Contract for Phase 3 Oral Antibiotic Development
26 Sep 2025 19:32 GMT
… development of its novel oral antibiotic, ceftibuten-ledaborbactam etzadroxil. The agreement … are often caused by multidrug-resistant Gram-negative bacteria, and effective … for serious infections caused by resistant bacteria.
Under the terms of …
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Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance
26 Sep 2025 01:39 GMT
… how plasmids adapted to the antibiotic era and the evolutionary journey … see the impact of human antibiotic use and the shadow of … to target the spread of antibiotic resistance genes, the consequences of which …
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Tracing a Century of Antibiotic Resistance Evolution
25 Sep 2025 19:46 GMT
… Lancet.
Keywords: Antibiotic resistance, Drug resistance, Bacteria, … resistance evolutioncentury-long antibiotic resistance trendscollaboration in antibiotic researchevolution of antimicrobial resistancegenetic mechanisms of multidrug resistanceglobal …