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Novel Non-Opioid Analgesic May Offer Hope Amid U.S. Opioid Crisis
07 Aug 2025 06:42 GMT
… central nervous system. However, drugs that broadly activate α2- … and development of an oral analgesic targeting the α2B adrenoceptor,” … trials at Kyoto University Hospital. In a Phase I trial … and ultimately make this treatment accessible to a broader …
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Vertex VX-993 Misses Primary Endpoint in Mid-Stage Trial, Ending Investigation for Acute Pain
06 Aug 2025 10:12 GMT
Vertex Pharmaceuticals announced Monday that … president, global medicines development and affairs, chief medical officer, … treatment-acute
Halsey G. FDA approves Journavx, first-in-class nonopioid analgesic … 47;trial-failure-of-vertexs-next-gen-pain-drug-mars- …
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Traffickers Exploit War Zones to Drive Illicit Drug Use
06 Aug 2025 10:10 GMT
… the total quantity of pharmaceutical opioids seized worldwide between … public health measures, including drug treatment.
“Without urgent and sustained … tramadol is an opioid analgesic that is used to … sold at higher doses than medical supplies.
“More than …
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Effects of Remimazolam-Propofol with Flumazenil Reversal on the Emergence Time and Hemodynamics of Patients Undergoing Laparoscopic Partial Hepatectomy: A Prospective Randomized Controlled Trial
06 Aug 2025 09:14 GMT
… perioperatively, and reduced analgesic requirements in laparoscopic … controlled trial comparing remimazolam with propofol. Drug Des … laparoscopic in the treatment of primary left … estimation of propofol in pharmaceutical formulations, biological matrices …
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FDA updates opioid pain medication labeling requirements
04 Aug 2025 19:18 GMT
… FDA announced required changes to safety labeling for all opioid pain medications … 39;s Anesthetic and Analgesic Drug Products Advisory Committee in … acting formulations or other treatments aren't … will be provided.
Drug–drug interactions. Labels must …
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After phase 3 hit, Spine seeks path forward for pain drug
04 Aug 2025 15:37 GMT
… 67% of patients in the treatment arm met the disability and … sites in the trial, according to the biotech, and stripping those … with alternatives to opioid-based analgesics for chronic pain indications … pain, with late-stage trials on the go in chronic …
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Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial
04 Aug 2025 11:05 GMT
… Pharmaceutical University granted ethical approval for this study (Medical … Trials (CONSORT)19 guidelines, ensuring complete and transparent reporting of all trial … analgesic preparation. Regarding the investigational drug … the intravenous treatment of acute …
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Medical-use contaminated fentanyl death toll rises to 68
04 Aug 2025 07:27 GMT
… of fentanyl produced by pharmaceutical company HLB Pharma and … drug, which is a powerful synthetic opioid, acts as an analgesic … except for one who began medical treatment in mid-December. No … related to the contaminated medication “is still under investigation …
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FDA Calls for Better Opioid Safety Labeling
04 Aug 2025 04:31 GMT
The FDA is requiring manufacturers of opioid pain medications to … and the Anesthetic and Analgesic Drug Products Advisory Committee, which … term use of opioid analgesics.
One of the … FDA has also called for a new prospective, randomized controlled trial …
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"Every Species On The Planet Self-Medicates In Some Way": How Wild Animals Use Medicine
04 Aug 2025 00:00 GMT
… our feet, or visit a doctor for an expert opinion – … case of active wound treatment using a biologically active … [the plant] has potent analgesic effects, Rakus may have felt … from animal “medicine”?
They might not have invented vaccines or mastered …