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Investornewsbreaks Oncotelic Therapeutics, Inc. (OTCQB: OTLC) Joint Venture Sapu Nano Receives Approval To Begin Phase 1 Trial Of Injectable Everolimus For Breast Cancer
25 Sep 2025 06:47 GMT
… joint venture through GMP Biotechnology Limited, Sapu Nano, … breast cancer. Everolimus, marketed as Afinitor(R), is FDA-approved … delivered intravenously, allowing full drug absorption into the bloodstream … oral version. The trial will determine optimal dosing …
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<![CDATA[Breast Cancer Experts: Key ADC Developments and CDK 4/6 Inhibitor Updates Set to Dominate ESMO 2025]]>
25 Sep 2025 16:11 GMT
… in the Division of Cancer Medicine at The University … cancer setting, where patients often face limited effective treatments … that mTOR inhibitor everolimus [Afinitor] can work [irrespective of … phase 3 monarchE trial [NCT03155997] trial looking at endocrine …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
25 Sep 2025 00:11 GMT
… GMP Biotechnology … FDA-approved drug (Afinitor®) for various cancers, including advanced breast cancer, kidney cancer … , and certain rare tumors. In oral pill … trials,” said Sapu Nano CEO, Dr. Vuong Trieu. “Despite advances in treatment …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
25 Sep 2025 00:00 GMT
… GMP Biotechnology … FDA-approved drug (Afinitor®) for various cancers, including advanced breast cancer, kidney cancer … , and certain rare tumors. In oral pill … trials,” said Sapu Nano CEO, Dr. Vuong Trieu. “Despite advances in treatment …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
24 Sep 2025 12:30 GMT
… clinical trial of Sapu003—an injectable form of Everolimus—for the treatment … drug (sold under the brand name Afinitor®) for various cancers, including advanced breast cancer, kidney cancer …
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<![CDATA[Giredestrant + Everolimus Delivers New Hope in ER+ Breast Cancer Post-CDK4/6 Treatment]]>
24 Sep 2025 00:43 GMT
… (Roche) and everolimus (Afinitor; Novartis) extends progression-free survival … 70% of breast cancer cases. Treatment with aromatase inhibitors, … be addressed rigorously by doctors through patient monitoring. … of taking the medicine orally.
REFERENCES
Positive …
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Angelini taps Sovargen for epilepsy drug in $550m deal
23 Sep 2025 12:32 GMT
… inhibitor from South Korean biotech Sovargen with potential for … couple of drugs in the class – Novartis' Afinitor (everolimus) and … the back of clinical trials showing they can … despite combination treatment of several anti-seizure medications. Our work …
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<![CDATA[Giredestrant Plus Afinitor Improves Outcomes in ER-Positive Breast Cancer]]>
22 Sep 2025 19:55 GMT
… .
The trial met its co-primary goals, showing that giredestrant plus Afinitor … in breast cancer
Giredestrant is an investigational, oral next-generation drug known … global phase 3 trials across different breast cancer stages and treatment settings to …
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<![CDATA[Giredestrant Combo Significantly Boosts PFS in ER+ Advanced Breast Cancer]]>
22 Sep 2025 21:15 GMT
Treatment with giredestrant plus everolimus (Afinitor) significantly prolonged … treatment with a CDK inhibitor,” Levi Garraway, chief medical … , phase 3 evERA trial assessed the safety and … metastatic breast cancer who received prior treatment with CDK4…
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<![CDATA[Giredestrant Plus Everolimus Meets Coprimary PFS End Points in Post–CDK Inhibitor ER+/HER2– Breast Cancer]]>
22 Sep 2025 20:43 GMT
… giredestrant plus everolimus (Afinitor) demonstrated a statistically … head phase 3 trial investigating an … at an upcoming medical meeting and subsequently … trials:
lidERA Breast Cancer (NCT04961996): Giredestrant vs SOC endocrine therapy as adjuvant treatment …