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The Role of Pyroptosis in Colorectal Cancer: From Mechanisms to Therapeutic Opportunities
11 Dec 2025 21:49 GMT
… in cancer cells tend to benefit more from 5-Fu based chemotherapy. Studies … , leucovorin and oxaliplatin; FOLFOXIRI, 5-fluorouracil, L-leucovorin, oxaliplatin and irinotecan … ; TNF, tumor necrosis factor; 5-FU, 5-Fluorouracil.
Funding
There is no funding …
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Annexin-A1 Modulates Apoptosis-Autophagy in Colorectal Cancer
10 Dec 2025 20:11 GMT
… in a model of 5-fluorouracil (5-FU)-resistant colorectal cancer. The findings highlight … indicating an adaptive response to chemotherapy. This elevation corresponds with changes … aiding cancer cells in surviving the harsh conditions induced by chemotherapy.
…
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Akari Therapeutics Highlights Preclinical Data Demonstrating Therapeutic Potential of Lead Candidate, AKTX-101, for Hard-to-Treat K-Ras Mutant Pancreatic Cancer
09 Dec 2025 13:40 GMT
… -Ras G12V-driven PDAC are 5-fluorouracil (5-FU) containing chemotherapy regimens such as FOLFIRINOX … non-small cell lung cancer and colorectal cancer further emphasizing the void … including lung and breast cancers. Within pancreatic cancer, K-Ras mutated PDAC …
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Case Report: Successful Surgical Resection of PVTT Vp4 Hepatocellular Carcinoma Following Hepatic Arterial Infusion Chemotherapy Combined with Cadonilimab Plus Donafenib
06 Dec 2025 09:36 GMT
… chemotherapy of liver tumors with 5-fluoro-2’-deoxyuridine (FUDR) and 5-fluorouracil (5-FU … ) in an animal model. J Cancer Res Clin Oncol …
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<![CDATA[Experts Say FDA Approval of Perioperative Durvalumab Plus FLOT Sets New Standard of Care for Early-Stage Gastric, GEJ Cancers]]>
04 Dec 2025 13:03 GMT
… leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy as a neoadjuvant and adjuvant … management of gastric and gastroesophageal cancer.
What should clinicians know … 3 drugs, oxaliplatin, docetaxel, and 5-FU [5-fluorouracil] that can cause side effects …
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Development and Validation of Nomogram Models Incorporating the Inflammatory Nutritional Index CALLY for Predicting Survival in Locally Advanced Rectal Cancer After Neoadjuvant Chemoradiotherapy
01 Dec 2025 10:49 GMT
… advanced colorectal cancer; NACRT, neoadjuvant chemoradiotherapy.
Treatment Strategies … oral (capecitabine) 5-fluorouracil chemotherapy-based chemotherapy. Radiotherapy was delivered … chemotherapy was as follows: the Roswell Park regimen of intravenous 5-FU …
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Lala Kent Shares a Health Update Months After Pre-Cancer Eye Diagnosis (EXCLUSIVE)
20 Nov 2025 19:54 GMT
… the months following her pre-cancer diagnosis in her eye.
The … opens up about her pre-cancer diagnosis
Lala has used social … to be pre-cancer. They immediately prescribed Lala with chemotherapy eye drops … . "It's called 5-FU and they paired it with …
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<![CDATA[Experts Highlight Notable Advances in Colorectal Cancer at 2025 ESMO ]]>
14 Nov 2025 03:47 GMT
… Organization Initiatives at Perlmutter Cancer Center, sat down to … to treating metastatic colorectal cancer. Cecchini emphasized that … through surgery combined with chemotherapy. Standard first-line … of which combine fluorouracil (5-FU) with other agents such …
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<![CDATA[NALIRIFOX Expands Frontline Options in Metastatic Pancreatic Cancer ]]>
11 Nov 2025 23:50 GMT
… liposome (Onivyde) plus oxaliplatin, 5-fluorouracil (5-FU), and leucovorin (NALIRIFOX) is … in pancreatic cancer.
Frontline Chemotherapy Regimens in Pancreatic Cancer: Key Takeaways … combination with chemotherapy regimens?
Over 90% of pancreatic cancers have …
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The Intricate Web of MicroRNAs in Modulating EGFR-TKI Resistance in Non-Small Cell Lung Cancer: A Comprehensive Review
11 Nov 2025 07:13 GMT
… in resistance to lung cancer treatments. Cancer Treat Rev. 2015;41 … cell-like properties in cancer cells. Cancer Res. 2013;73(10 … nucleic acids and anti-cancer drugs for chemoresistance reversal. Int J … Ju J. Development of a 5-FU modified miR-129 mimic as …
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