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Doctors warn Korea is falling behind global standards in AL amyloidosis treatment
22 Sep 2025 04:31 GMT
… standard treatment.
In this regard, the DVCd (daratumumab, velcade, … of two or three doctors before receiving a diagnosis … Professor Kim, at Samsung Medical Center, only 5- … treatment.
Yet Korea remains stuck in place. Caught between the pharmaceutical …
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<![CDATA[Belantamab Mafodotin/Bortezomib/Dexamethasone Yields PFS, OS Benefits in Lenalidomide-Refractory Myeloma ]]>
20 Sep 2025 01:09 GMT
… belantamab mafodotin-blmf (Blenrep), bortezomib (Velcade), and dexamethasone (BVd) produced … and associate professor of medicine in the Hematology … of the DREAMM-7 Trial Subgroup Analysis?
The randomized … by-the-us-fda-for-the-treatment-of-relapsedrefractory- …
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Beyond the Diagnosis: A Stage-by-Stage Guide to Multiple Myeloma Treatment
18 Sep 2025 17:29 GMT
… trial. These trials investigate whether early treatment … drug classes used in these combinations include:
Proteasome inhibitors: (e.g., Velcade [bortezomib … prevent fractures.
Medications to manage anemia … a particular treatment, your doctor may consider …
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<![CDATA[CEPHEUS Highlights Efficacious, Safe Regimen for Transplant-Ineligible/Deferred Multiple Myeloma]]>
21 Sep 2025 15:27 GMT
… trial (NCT03652064)
evaluating subcutaneous daratumumab (D; Darzalex) plus bortezomib (Velcade), … assistant professor of medicine at Harvard Medical School and the … that issue.
Both doctors agreed that with the … ” as a long-term treatment. “Ultimately, it is …
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<![CDATA[Isa-VRd Meets Primary End Point in Transplant-Ineligible Newly Diagnosed Multiple Myeloma]]>
20 Sep 2025 20:09 GMT
… as a flat dose plus bortezomib (Velcade), lenalidomide (Revlimid), and dexamethasone … , 4 patients had discontinued treatment, no relapses had been … AEs occurred in 45%. Drug-related AEs of grade 3 … were reported in this trial.
Infusion reaction was observed …
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J&J’s newly diagnosed multiple myeloma induction combo elicits 100% OR
20 Sep 2025 02:08 GMT
… trial (NCT05695508) show that 100% of patients achieved OR after treatment … Food and Drug Administration (FDA) in October … Currently, initial treatment for multiple myeloma includes Velcade (bortezomib), Revlimid … ! The Clinical Trials Arena Excellence Awards …
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Comorbidities May Influence Teclistamab Induction Regimen Use in NDMM
19 Sep 2025 07:58 GMT
… -5 trial, investigators combined teclistamab with agents such as daratumumab (Darzalex), bortezomib (Velcade … Center and the Department of Medicine V at the Heidelberg University … profile of teclistamab-based treatment in this trial was expected based on …
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<![CDATA[D-VRd Produces Favorable PROs and Safety Outcomes in MRD-Negative Newly Diagnosed Multiple Myeloma]]>
20 Sep 2025 01:10 GMT
… (MRD) negativity following treatment with daratumumab (Darzalex) plus bortezomib (Velcade), lenalidomide (Revlimid), … April 2024, the FDA’s Oncologic Drugs Advisory Committee voted 12 … clinical trials.2 “In May [2025], the Committee for Medicinal Products …
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<![CDATA[BKd Produces Robust Responses in Relapsed/Refractory Multiple Myeloma]]>
21 Sep 2025 01:48 GMT
… BCMA-directed antibody-drug conjugate belantamab mafodotin- … therapy (P = .5763), bortezomib (Velcade)–refractory disease (P = .1596 … were off treatment. Patients discontinued treatment due to … Australian New Zealand Clinical Trials Registry. Updated April …
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<![CDATA[Belantamab Mafodotin/Lenalidomide Maintenance Displays Manageable Eye Toxicity Profile in Newly Diagnosed Myeloma]]>
21 Sep 2025 01:48 GMT
Treatment with 2 years of … GEM-Bela-VRd trial (NCT04802356) of belantamab mafodotin plus bortezomib (Velcade), lenalidomide, and … , multicenter, nonrandomized, single-arm trial enrolled patients at least 18 … every 8 weeks plus VRd (bortezomib at 1.3 mg…