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<![CDATA[US Survey Reveals Underuse of Dravet Syndrome–Specific Antiseizure Medications in the Clinic]]>
07 Dec 2025 01:40 GMT
… survey, findings showed that valproate (47%) and clobazam ( … limited access, dosing, drug-drug interactions, and lack of … as the rationale for treatment decisions. Following survey … care influences antiseizure medication selection, although discrepancies …
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<![CDATA[Dravet Syndrome Medication Stiripentol Effective in Real World Settings Across Various Patient Profiles]]>
05 Dec 2025 20:58 GMT
… at Mayo Clinic, treatment with the FDA-approved medication led to significant reductions … dosage or concomitant clobazam or valproate use.
The real-world study … about potential improvements to the drug’s delivery, such as developing …
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A popular “essential” medicine may be putting unborn babies at risk
28 Nov 2025 16:57 GMT
… Health Organization lists valproate as an essential medicine, yet the drug can lead … are gaining access to antiseizure medications, these treatments are not always being … to essential neurological treatments. However, they also found that valproate remains the …
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Despite Risks, Safety Warnings, Valproate Use On the Rise
19 Nov 2025 19:26 GMT
… , valproic acid (valproate) remains the most widely prescribed antiseizure medication globally, with … global pharmaceutical sales data, Chan and colleagues examined trends in antiseizure medication … decline in use of older drugs, such as phenobarbital (-2.9% …
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Phase 3 trial Demonstrates 63% Reduction in Schizophrenia Relapse Risk
19 Nov 2025 13:20 GMT
… disorder in conjunction with antidepressants, as well as … or valproate.
A supplemental New Drug Application for the medication’ … under FDA review. An additional application for adjunctive treatment … randomized withdrawal, phase 3 trial. Poster presented at: …
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Scientists Warn That This “Essential” Medicine Can Cause Birth Defects
18 Nov 2025 21:59 GMT
… drugs is rising, but so are concerns about a widely used medicine … medications is expanding in low- and middle-income countries, these drugs … most commonly prescribed drug, valproate, can cause … treatment options. But the continued widespread use of valproate …
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Clinical Efficacy and Safety of Auricular Acupuncture for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
17 Nov 2025 20:41 GMT
… drugs (eg, topiramate, valproate), and tricyclic antidepressants … medication and the side effects of long-term drug treatment … trials (mean 85 participants per trial … pills in the treatment of blood stasis migraine. Beijing University of Chinese medicine …
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<![CDATA[NBI-827104’s Phase 2 Disappointment Highlight Therapeutic Needs for Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep]]>
05 Dec 2025 20:58 GMT
… channel blocker, as a treatment for patients with epileptic … a condition with no FDA-approved medications.1
The results, which … currently no late-stage drug trials for EE-CSWS at … , while other therapies like valproate, levetiracetam, and lamotrigine have …
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Clozapine Drug–Drug Interactions and Individualized Dosing in Bipolar Disorder: A Model-Informed Precision Dosing Approach
13 Nov 2025 22:56 GMT
… sodium valproate sustained-release tablet, sodium valproate tablet … precise medication intervention in complex medication scenarios … trial with clozapine?: therapeutic drug monitoring and time to response in treatment … Dosing (MIPD). Pharmaceutics. 2022;14(12 …
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Valproate Use in Pregnancy May Cause Developmental Disorders
12 Nov 2025 11:19 GMT
… equitable use of essential neurological medicines worldwide.
The study used sales … better understanding of whether such drugs are being prescribed to women … or no treatment options. But the continued widespread use of valproate in …