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    • Torcetrapib

Torcetrapib Newsletter
  • The best report on why it’s unsafe for the FDA to skip phase 3 trials comes from the FDA 02 Sep 2020 20:45 GMT

    … on the safety of a drug or treatment, but they cannot deliver … trials. Just like Phase 1 and Phase 2, the Phase 3 trial … and immunity. As the FDA noted when reporting on these … from heart disease (aliskiren, darapladib, torcetrapib) to Staph infection (V710 …

  • This Is A Heart Drug That The World Doesn’t Need 27 Aug 2020 13:28 GMT

    … , in early clinical trials, these drugs totally remodeled a heart … interest in these drugs as well. Statins were major commercial … torcetrapib and, in some ways, they were. However, these drugs … 30,000 patient outcomes trial. The FDA has required other …

  • The Master Key To Drug Design: Multi-Target Drugs 16 Sep 2019 15:03 GMT

    drug have more than halved since 2010. The pharmaceutical … pharma, including academia, biotech and big pharma to … target medicines. For these diseases, standard treatment often involves multi-drug … 800 million was spent on Torcetrapib, and Pfizer’s stock …

  • How Will The Failure Of Biogen's Alzheimer's Drug, Aducanumab, Impact R&D? 22 Mar 2019 13:52 GMT

    trial with aducanumab due to a futility analysis showing that the drug … in this potential breakthrough treatment, not just in Pfizer … that torcetrapib failed its long-term clinical study. The drug … requires long, expensive clinical trials. Finally, it wouldn’t …

  • Pharma Failures Actually Advance Medicine 17 Oct 2018 10:09 GMT

    … , one doesn’t enter pharmaceutical R&D if he … experimental medicines that enter human trials actually results in an FDA approval … Lowe focuses on is torcetrapib, a drug designed to raise HDL … LDL-cholesterol on top of statins. Some even dreamed that …

  • Harvard Professor's Attack On Pharma's Clinical Trials Is Absurd 19 Sep 2018 05:18 GMT

    trials PAID FOR by pharmaceutical companies but run at major medical … is. Pfizer’s ILLUMINATE trial, designed to prove the … drug, torcetrapib, failed. The study, however, answered a major medical … . While these drugs, in combination with statins, lowered LDL- …

  • Will Merck Seek FDA Filing For Heart Drug After Lackluster Results? 29 Aug 2017 15:52 GMT

    torcetrapib), Roche (dalcetrapib), and Eli Lilly (evacetrapib) failed massive clinical trials … class of cholesterol-lowering medicines called PCSK9 inhibitors. Yet … on the Merck drug and statins had a total … Xconomy's Deputy Biotechnology Editor. You can …

  • Merck's anacetrapib rescued by positive phase III trial 28 Jun 2017 12:07 GMT

    … results in a phase III trial. Optimism for the CETP … three other drugs in the class - Pfizer's torcetrapib, Roche … cardiovascular events when added to statins in patients with elevated cholesterol … . Merck's chief medical officer Roy Baynes told the …

  • Merck heart drug surprises with positive result; questions linger 27 Jun 2017 16:55 GMT

    drug, anacetrapib, met the main goal in the 4-year trial … bets ... suggests that the treatment effect may have been relatively … been banking on its torcetrapib to replace lost revenue when … most expensive failure in pharmaceutical history in late 2006, when …

  • Merck's Magic Touch Extends To High-Risk Heart Drug 27 Jun 2017 17:50 GMT

    … LDL lowering HDL raising Trial ID Torcetrapib Pfizer Illuminate 15,067 … problems who were already on statins, and followed them to … win with high risk heart drug, January 19, 2017). Merck … not historically prevented the pharmaceutical industry from having a …

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