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Fierce Pharma Asia—BMS’ China asset sale; 2 biotech debuts; 2 potential deals
20 Sep 2025 01:33 GMT
… are reportedly eyeing an antibody-drug conjugate deal with Henlius. … cardiovascular biotech, offers Mabwell up to $1B for siRNA asset
… Kalexo will develop the drug for dyslipidemia and high-risk … -patient trial showed the drug reduced seizure frequency by …
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China’s Mabwell and US-based Aditum Bio ink $1 B deal for siRNA cardiovascular therapies
19 Sep 2025 22:50 GMT
… 2MW7141, a novel dual-target siRNA candidate for lipid management in … , a novel dual-target siRNA candidate for lipid management in … unmet need. To speed these drugs to market, Aditum Bio … on the translational phase of drug development. This model enables a …
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Mabwell and Aditum Bio Launch Kalexo Bio to Develop siRNA Cardiovascular Therapies
19 Sep 2025 11:59 GMT
… the formation of a new biotech company, Kalexo Bio, focused … a novel dual-target siRNA candidate designed for lipid … therapeutic approach targeting multiple genetic pathways involved in lipid … incubator-style model for drug development, will provide full …
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Kalexo enters dyslipidemia fray with preclinical siRNA candidate
18 Sep 2025 23:39 GMT
Mabwell Bioscience Co. Ltd. and Aditum Bio Management Co. LLC announced, in after-market hours Sept. 17, an agreement to forge a new company called Kalexo Bio Inc. and load the biotech with a preclinical dyslipidemia asset via a potential $1 billion global …
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Mabwell and Aditum launch Kalexo Bio for siRNA therapy development
18 Sep 2025 10:44 GMT
… a new small interfering RNA (siRNA) candidate, 2MW7141.
The … to advance this promising siRNA therapy into the clinic.” … received the US Food and Drug Administration (FDA) fast … track designation for its antibody-drug conjugate (ADC), 9MW2821, targeting …
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Joe Jimenez's new biotech inks up to $1B biobuck deal for Mabwell's cardio siRNA
17 Sep 2025 13:51 GMT
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Choosing China: Akeso’s $3M Beginnings and the Rise of China’s Biotech Sector
17 Sep 2025 07:00 GMT
… partnership with California-based Summit Therapeutics, which in December 2022 … ” for antibody drug development with a global pharma company, she … to Xia, the Chinese biotech sector provides a “conducive … , such as mRNA and siRNA therapies, as well as …
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Rona Therapeutics seeks IND clearance for RN-3161 for obesity
16 Sep 2025 23:01 GMT
Endocrine/metabolic
Rona Therapeutics Co. Ltd. has announced an … obesity. RN-3161, a novel siRNA developed through Rona’s proprietary …
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New self-assembling nanoparticles could transform drug delivery
16 Sep 2025 20:07 GMT
… wide variety of biological drugs.”
From problem to platform … key to protecting delicate drugs like RNA and proteins … to real-world vaccine or drug delivery challenges.
Citation: “Thermoreversibly … and Delivery of Protein and siRNA Biologics,” Hossainy et al, …
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ADARx Pharmaceuticals Appoints Industry Veteran, Laura Shawver, Ph.D., as Board Chair
17 Sep 2025 13:00 GMT
… is a late-stage clinical biotechnology company dedicated to transforming cutting … the treatment of complement-mediated, genetic, cardiovascular, thrombosis, central nervous … to develop small interfering RNA (siRNA) therapeutics across multiple disease areas, …