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EMA grants Orphan Drug Designation to Ribo's siRNA therapeutic RBD1016 for Hepatitis Delta Virus infection
25 Oct 2025 11:35 GMT
… technology and industrialization of oligonucleotide drugs, and Ribocure Pharmaceuticals AB ( … of the programs, where the siRNA drug candidate is designed to selectively … a globally integrated drug development capability and a rich siRNA pipeline.
Ribocure …
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GSK and Empirico enter license agreement for clinical-stage, first-in-class oligonucleotide candidate to treat respiratory diseases
28 Oct 2025 07:22 GMT
… biotechnology company with leading capabilities in human genetics-driven target discovery and siRNA … need.”
Oligonucleotides, such as siRNA therapeutics, have a distinct ability to … targets to clinically-viable therapeutics. Empirico’s exceptional internal …
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Prospects and Challenges of Chitosan-Based Drug Carriers for Anticancer Agents’ Delivery Against Lung Cancer: A Review
24 Oct 2025 14:10 GMT
… related deaths, while genetic susceptibility, occupational exposures … chemotherapeutic drugs with siRNA in nanoscale drug delivery systems … for cancer nano drug delivery. Biotechnol Adv. 2023;67 … development of anticancerous therapeutics. Front Nutr. …
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Takeda signs deal worth up to $11.4bn with Innovent for cancer drug hopefuls
23 Oct 2025 11:24 GMT
… chain of big pharma companies currently betting on innovative drugs developed in … Biopharma’s small interfering RNAs (siRNA) for severe hypertriglyceridemia (sHTG) and … limit the capacity of Chinese biotechs and manufacturing companies to obtain …
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Novartis Delivers Solid Sales And Core Operating Income Growth With Strong Pipeline Progress In Q3 Reaffirms FY 2025 Guidance
28 Oct 2025 07:26 GMT
… collaboration with Monte Rosa Therapeutics, in addition to the … exclusive license to an siRNA candidate currently in IND- … license two second-generation siRNA molecules currently in development, … SNCA, a preclinical-stage siRNA therapy targeting alpha-synuclein …
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Beyond Antibodies: Unlocking New Targets and Applications with Optimer
27 Oct 2025 20:38 GMT
… eBook
Across biomedical research and drug development, the boundaries of possibility … biomarker landscapes or enabling precision drug delivery.
This potential is already … as selective delivery vehicles for siRNA, demonstrating precise targeting of activated …
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Ferroptosis-Related Gene CRYAB in Asthma: Bioinformatics Identification and Experimental Validation
25 Oct 2025 18:55 GMT
… were synthesized by Sangon Biotech (Shanghai, China). Ferroptosis … ferroptosis. (a–c) siRNA-mediated knockdown of CRYAB … providing new biomarkers and drug targets for the diagnosis … biology and therapeutics: type 2 targeted therapeutics for adult asthma …
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The Dual Role of the TRAIL-DR5 Signaling Axis in Cardiovascular Disease: From Molecular Mechanisms to Targeted Therapies
25 Oct 2025 13:48 GMT
… of Bioymifi and chemotherapy drugs (such as doxorubicin) … on multi-dimensional biomarkers (genetic variation, metabolic characteristics, … from mechanisms to targeted therapeutics. Acta Pharmacol Sin. 2023 … in Escherichia coli. Mol Biotechnol. 2023;65(4):581 …
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Identification and Validation of Lipid Metabolism-Related Biomarkers GPD1 and CEBPD in Metabolic Dysfunction-Associated Steatohepatitis
25 Oct 2025 08:41 GMT
… a scrambled control siRNA, were obtained from Wuhan Hewu Biotechnology Co., Ltd … -Sample Gene Set Enrichment Analysis; siRNA, small interfering RNAs; qPCR, … dehydrogenase 1. Am J Hum Genet. 2012;90:49–60. … related to GPD1 gene. Front Genet. 2022;13:916672. doi: …
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Aqueous Humor Metabolomics in Different Stages of Diabetic Retinopathy Based on Ultra - Performance Liquid Chromatography - Tandem Mass Spectrometry
25 Oct 2025 08:42 GMT
… was performed by Beijing Qinglian Biotech, Co., Ltd.
Data Processing and … anti-vascular endothelial growth factor drugs.19 However, when retinopathy progresses … methylation inhibitors (azacytidine or dnmt1-siRNA) prevented hypermethylation of the mismatch …