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RNA drug developer Ribo Passes Hong Kong Listing Hearing, Kicking Off IPO
26 Dec 2025 13:20 GMT
… in RNA-based nucleotide drug development, the Suzhou-based … using small interfering RNA (siRNA), which block the … largest siRNA pipelines, including seven clinical-stage candidate drugs aimed … between 2024 and 2029. SiRNA drugs already account for approximately …
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Samyang Biopharm secures KDDF backing for IPF drug development
22 Dec 2025 07:13 GMT
… jointly develop a candidate drug for idiopathic pulmonary fibrosis … , to deliver therapeutic genetic material more precisely and … generation RNA-based therapeutics, such as siRNA (short interfering RNA … #39;s pharmaceutical and biotech industry.
Launched in 2021 …
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Targeted-Immunomodulatory Nanomedicines for the Treatment of Autoimmune Diseases via Multiple Administration Routes
27 Dec 2025 01:44 GMT
… for delivery of genetic drugs. Nature Rev Mater. … using nanoparticle encapsulated siRNA mitigates viral and autoimmune … nanoparticle vaccines. Nature Biotechnol. 2007;25(10):1159 … SJ, Phee H. Emerging therapeutics for immune tolerance: tolerogenic …
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Engineered Nanoparticles: Targeting Endocrine Tumors Advances
26 Dec 2025 19:47 GMT
… ; polymeric carriers provide controlled drug release mechanisms; and inorganic … doxorubicin-loaded nanoparticles or siRNA formulations have shown promise … nanoparticles for cancer treatmentenhancing drug delivery with nanoparticlesligands for …
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Neutrophils Extracellular Traps Impair Lung Endothelial Proliferation in Sepsis via PLK1 Inhibition and Cell Cycle Arrest
26 Dec 2025 14:44 GMT
… serum albumin (WB6504, NCM Biotech, Shanghai, China) for 60 … Evans blue dye (Sangon Biotech, Shanghai, China) through … Germany). Custom-designed primers (Tsingke Biotech, Beijing, China) were employed … Impact of anti-PLK1 siRNA-containing F3-targeted liposomes …
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Neuregulin-1 Secreted by Cancer-Associated Fibroblasts Promotes Growth of Triple-Negative Breast Cancer
26 Dec 2025 09:16 GMT
… Kit (Cat# EH1972, Wuhan Fine Biotech Co., Ltd., Wuhan, China). … secreted NRG1 concentrations after siRNA knockdown compared with untreated … receptors in breast cancer. Drug Des Devel Ther. 2022 … breast cancer (TNBC): non-genetic tumor heterogeneity and immune …
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Co-Targeting Biomimetic Nanoparticles Alleviate Atherosclerosis by Inhibiting the Vicious Circle Between Inflammation and Lipids
25 Dec 2025 08:36 GMT
… 7 weeks old, Chengdu Pharmachem Biotechnology, Chengdu, China) received a … Potential, Encapsulation Efficiency, and Drug Loading Capacity
Typically, the … cell-targeting, ROS-ultrasensitive drug/siRNA co-delivery nanocomplexes mitigate early …
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Construction of 3D Enhanced CT Radiomics-Based Model to Predict Circadian Gene Expression and Prognosis in Hepatocellular Carcinoma
24 Dec 2025 17:16 GMT
… test the hypothesis that genetically predisposed circadian disruption … specific interference sequences of siRNA used were as follows … and current and future drugs. J Clin Exp Hepatol … randomization analyses with multiple genetic variants. Epidemiology. 2017; …
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Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Nanovesicles Alleviated Colitis via Modulating Th17/Treg Balance Through Hsa-miR-27b-3p-Mediated Suppression of PI3K/AKT/STAT3 Signaling Pathway
24 Dec 2025 17:16 GMT
… mRNAs, microRNAs, and other genetic materials, into recipient cells … serum (FBS, Hangzhou Yangming Biotechnology Co., LTD., Hangzhou, … class of immunomodulatory therapeutics that effectively ameliorate colitis … hydrogel for local drug delivery in inflammatory …
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Phio To Commence A Toxicology Study For PH-762; Initiatives Underway For A Viable Product In 2026
24 Dec 2025 12:20 GMT
… (PHIO), a clinical-stage siRNA biopharmaceutical, announced that it has … pivotal trial in its drug development program for PH … entered into a comprehensive drug substance development services agreement … step toward advancing the drug development pathway for PH …