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Repurposed Diabetes Drug Primes CAR T-Cell Therapy Cancer Targets
17 Sep 2025 09:11 GMT
…
The first FDA-approved antibody-drug conjugate therapy … patients whose malignancy is treatment resistant, meaningful improvement … repurposed older diabetes drugs, including rosiglitazone and pioglitazone, both … led by former UCSF medical student Kevin Chang, …
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CYP2C8-Mediated Drug–Drug Interactions and the Factors Influencing the Interaction Magnitude
16 Sep 2025 09:22 GMT
… who was receiving eight medications (metformin, pioglitazone, sitagliptin … to comedicate with statins.85
Antidepressants
Fluvoxamine is … rosiglitazone between control and TFE groups. The TFE treatment … and clinical pharmaceutical care. Develop new drugs that …
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Repurposed diabetes drugs boost CAR T therapy effectiveness in bladder cancer
13 Sep 2025 02:33 GMT
… .
The first FDA-approved antibody-drug conjugate therapy for … patients whose malignancy is treatment resistant, meaningful improvement in … old class of diabetes drugs – rosiglitazone and pioglitazone – which … led by former UCSF medical student Kevin Chang, MD …
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Obesity and Its Comorbidities: Current Treatment Options, Emerging Biological Mechanisms, Future Perspectives and Challenges
11 Sep 2025 19:59 GMT
… rosiglitazone and pioglitazone are clinically used as promising drug … and Drug Administration (FDA) approved five medications for … Pharmacological treatment of MASLD: contemporary treatment and future … controlled, multicentre clinical trial. Trials. 2023;24:283 …
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Repurposing a Diabetes Medication to Prime CAR T Cancer Targets
10 Sep 2025 23:23 GMT
…
The first FDA-approved antibody-drug conjugate therapy for … whose malignancy is treatment resistant, meaningful improvement … old class of diabetes drugs – rosiglitazone and pioglitazone – … reflecting the latest medical knowledge, advanced technologies …
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UCSF is combatting treatment resistant metastatic urothelial carcinoma
11 Sep 2025 03:06 GMT
… working to combat treatment resistant metastatic urothelial carcinoma … it with the diabetes treatment “thiazolidinediones.” The goal … T therapy.”
The treatment showed favorable results, … “Our strategy of repurposing rosiglitazone to prime NECTIN4 expression …
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Drug-Drug Interactions and Initial Dosage Optimization of Quetiapine in Patients with Depression: A Real-World Study
09 Sep 2025 10:53 GMT
… , pharmacotherapy with antidepressant medications is the primary treatment method.9–11 … hyperactive delirium: randomized controlled trial. Neurocrit Care. 2024;41 … substrate rosiglitazone and its metabolite to predict metabolic drug-drug interaction. Drug …
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Traditional Chinese Medicine Natural Products Targeting Shared Mechanisms of T2DM and AD: Potential Therapeutic Insights
03 Sep 2025 20:34 GMT
… 34 The insulin sensitizer rosiglitazone can improve IR … insufficient efficacy of medications, affecting clinical treatment outcomes and … endoplasmic reticulum stress. 3 Biotech. 2020;10(8):359 … induced diabetic albino rats. Pharmaceuticals. 2022;15(10):1205 …
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Effects of Brown Rice, Meal Replacements, and Anti-Obesity Drugs on Mitochondria in Obese Rats
01 Sep 2025 13:24 GMT
… Laboratory, Faculty of Medicine, Universitas Brawijaya.
Gut … PPAR-γ agonists like rosiglitazone, have been shown to … as well as pharmacological treatment with thiazolidinediones (TZDs), … mitochondria interactions. Clinical trials translating these preclinical …
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Oral Antidiabetic Drugs Market to Reach $86.92 Billion by 2029 with 6.8% CAGR
22 Aug 2025 18:03 GMT
… medical treatments, drugs, or procedures. For example, Eli Lilly and Company, an American pharmaceutical … stage 3 trial. This daily … . During clinical trials, orforglipron reduced … By Thiazolidinediones: Pioglitazone, Rosiglitazone
6) By Meglitinides: …