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Future Forward: Advancing SCAC Treatment Through Innovation and Access
18 Jul 2025 20:48 GMT
… the FDA approval and NCCN endorsement of retifanlimab plus carboplatin/paclitaxel … advanced squamous cell anal carcinoma treatment while highlighting future therapeutic opportunities … E6/E7, and antibody-drug conjugates, emphasizing the critical need …
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US FDA grants breakthrough therapy designation to Daiichi Sankyo & AstraZeneca’s Enhertu plus pertuzumab to treat unresectable or metastatic HER2 positive breast cancer
18 Jul 2025 08:35 GMT
… HER2 directed DXd antibody drug conjugate (ADC) discovered … endpoint over available medicines.
The FDA granted this BTD … or paclitaxel], trastuzumab and pertuzumab) as a first-line treatment … -Lung01 and DESTINY-CRC02 trials. Continued approval for this …
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Harnessing Organoid Platforms for Nanoparticle Drug Development
17 Jul 2025 18:58 GMT
… ), Lipusu™ (paclitaxel liposome), and Genexol-PM™ (paclitaxel polymeric micelle), … . Adv Biochem Eng Biotechnol. 2022;179:343–354 … in cancer immunotherapy. Pharmaceutics. 2023;15(3):775 … patient-specific response to drug treatment. Cancers. 2020;12 …
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Expanding Treatment Options for Ovarian Cancer
17 Jul 2025 14:35 GMT
… primary endpoint.
Unfortunately, the trial was negative: There was … unmet need is better treatment options for our patients … is mirvetuximab, an antibody-drug conjugate targeting the folate … ROSELLA trial were presented. All patients received nab-paclitaxel, an …
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Lisata Therapeutics and WARPNINE Announce iLSTA Trial Enrollment Completion and Provide Preliminary Data Update
17 Jul 2025 12:00 GMT
… pharmaceutical company developing innovative therapies for the treatment … and Development and Chief Medical Officer of Lisata. … SoC chemotherapy (nab-paclitaxel and gemcitabine) plus … drug candidates, the timing for starting and completing clinical trials …
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The Role of Preventive Nursing Interventions in Reducing Treatment-Related Complications in Ovarian Cancer Patients: A Retrospective Cohort Study
17 Jul 2025 11:30 GMT
… evaluation in clinical trials.3 Despite therapeutic … carefully tracked any adverse drug reactions.
The observation … confidence. Throughout the treatment, medical staff closely monitored … demonstrate that carboplatin-paclitaxel treatment can lead to serious …
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Assessing ADC Combinations for Treatment in Breast Cancer
17 Jul 2025 00:56 GMT
… NCT05382286) trials show promising activity when combining antibody-drug conjugates ( … [and] the ASCENT-04 trial, with first-line sacituzumab … for the first-line treatment of metastatic triple- … with cyclophosphamide, carboplatin with paclitaxel, etc. It’s a …
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FDA’s Published CRLs Deliver Insight Into the Drug Approval Process
16 Jul 2025 17:44 GMT
… drug developer perform an additional adequate, well-controlled, randomized clinical trial … with paclitaxel, … Pharmaceuticals, Inc. and Shilpa Medicare … Pharmaceuticals receives FDA approval for Lymphir (denileukin diftitox-cxdl) immunotherapy for the treatment …
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FDA Receives sNDA for Relacorilant in Platinum-Resistant Ovarian Cancer
15 Jul 2025 21:14 GMT
… 3 ROSELLA trial (NCT05257408), as well as phase 2 trials. It was … drug applications before the FDA: relacorilant in combination with nab-paclitaxel as a treatment … phase 2 trials: the completed phase 2 CORT125134-552 trial (NCT03776812), which …
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Arcus Biosciences’ quemliclustat receives US FDA orphan drug designation to treat pancreatic cancer
16 Jul 2025 01:23 GMT
… Drug Administration for the treatment of pancreatic cancer.
“The orphan drug … Markus, MD, chief medical officer at Arcus Biosciences. … trials, exemption from user fees including New Drug … gemcitabine/nab-paclitaxel chemotherapy versus gemcitabine…