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<![CDATA[Trabectedin Plus Olaparib Improves PFS in Some Patients With STS]]>
22 Dec 2025 19:15 GMT
… and olaparib (Lynparza; AstraZeneca, Merck) may be a meaningful treatment for … to guide therapy.
One treatment option for advanced STS … , a phase 2 randomized trial, the investigators tested the … failure of anthracycline-based treatment (TOMAS2): a randomized …
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Biosplice Therapeutics Announces First Patient Dosed in Investigator‑Initiated Phase 1 Clinical Trial of Cirtuvivint and Olaparib in BRCA/HRD Platinum‑Resistant Ovarian Cancer
22 Dec 2025 11:00 GMT
… Biosplice”), a clinical-stage biotechnology company advancing small-molecule … -initiated trial, “Cirtuvivint and Olaparib for the Treatment of … University School of Medicine
About Cirtuvivint
Cirtuvivint … inhibitors. Biosplice’s drugs in clinical development …
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<![CDATA[Stage 4 Pancreatic Cancer Survivor Shares Clinical Trial Path]]>
18 Dec 2025 20:17 GMT
… pursue an experimental treatment?
I did two clinical trials. The first … Keytruda (pembrolizumab) and Lynparza (olaparib) for about two years, and … one was an early-stage trial. Both of them were … that involves seeing other doctors, no doctor should be upset that …
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<![CDATA[FDA Grants Regular Approval to Rubraca for Some With Prostate Cancer]]>
18 Dec 2025 02:53 GMT
… and Drug Administration has granted regular approval to treatment with … the trial, Rubraca was associated with what the FDA described … inhibitors, such as Lynparza (olaparib) and Rubraca, were initially … agent therapies for the treatment of patients with …
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Real-World Study of Olaparib in Chinese Ovarian Cancer
18 Dec 2025 01:50 GMT
… Among these innovative treatments, olaparib has emerged as … prospective, non-interventional drug intensive monitoring study conducted … olaparib performs outside the controlled environment of clinical trials … emphasis on personalized medicine, the findings from …
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AZ's ATR inhibitor ceralasertib flunks lung cancer test
22 Dec 2025 17:11 GMT
… survival, although the dual treatment was well-tolerated.
ATR … inhibitor drugs, including AZ's pioneering Lynparza (olaparib), for … berzosertib, which started clinical trials in 2020 and has … committed to pioneering new medicines to address the urgent …
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ENHERTU® (fam-trastuzumab deruxtecan-nxki) plus pertuzumab approved in the US as first new treatment in a decade for the 1st-line treatment of patients with HER2-positive metastatic breast cancer
16 Dec 2025 03:09 GMT
… Food and Drug Administration (FDA)-approved …
In the trial, ENHERTU in … medicine camizestrant.
PARP inhibitor olaparib is a targeted treatment … BIOTECHNOLOGY HEALTH WOMEN PHARMACEUTICAL ONCOLOGY OTHER SCIENCE RESEARCH GENETICS CONSUMER SCIENCE CLINICAL TRIALS …
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<![CDATA[RAD51 Test Predicts Olaparib Response in HER2– Breast Cancer]]>
15 Dec 2025 15:13 GMT
… from the phase 2 RADIOLA trial (NCT05340413) demonstrates that a … 82.3%), respectively.
“This trial supports the value of a … a biopsy was performed after treatment. Patients with HR-positive … of treatment in both cohorts, clinical benefit with olaparib by …
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Synergistic Effects of HER2 Antibody and Olaparib
14 Dec 2025 11:34 GMT
… in therapeutic outcomes.
Olaparib, a PARP inhibitor, … trends towards personalized medicine.
While the findings … progresses into clinical trials, the oncology community … therapiesbreast cancer treatment advancementsHER2-positive cancer treatmentimproving patient …
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<![CDATA[RAD51-Based HRD Test Could Help Refine Patient Selection for Olaparib in BRCA1/2- or PALB2-Mutant, HER2– Breast Cancer ]]>
13 Dec 2025 05:25 GMT
… more likely to benefit from treatment with olaparib (Lynparza), according to data … of the phase 2 RADIOLA trial (NCT05340413).1
Findings presented at … .9%-82.3%), respectively.
“This trial supports the value of a …