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Identifying the genetic basis and molecular mechanisms underlying phenotypic correlation between complex human traits using a gene-based approach
23 Sep 2025 03:59 GMT
… -phenotype association profile to gene-phenotype association profile using … number of causal genes, and for each gene assign a … menarche are significantly overweight/obese [54]; 2) it was … #47;childhood-obesity subtree, we found overlapping genes in each of …
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Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning
22 Sep 2025 19:09 GMT
… βobese-DEGAS cells with the corresponding T2D and obesity trajectory genes … implicated as a diabetes risk gene and is important for … directionality of T2D or obesity gene associations agreed between DEGAS … FXYD2 is a downregulated gene in T2D in Marselli …
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Weighing in on how to manage obesity
22 Sep 2025 18:10 GMT
… .
Obesity is caused by a combination of factors: genetics, … obese.
That’s a deeply alarming statistic, especially considering that obesity … science-based approaches to obesity care.
“Through this … can take control and manage obesity more effectively.
* * *
…
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Genes or junk food? How metabolic obesity silently threatens health in India
20 Sep 2025 19:30 GMT
… WHO. The number of obese children and adolescents aged … could be overweight or obese. The sharpest rises are … weight loss in non-diabetic obese adults, improving blood pressure, … Surgery, explains, “Obesity is influenced by both genetics and lifestyle. About …
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Humanity's Weighty Story: From ancient slenderness to a fat crisis triggered by genes
20 Sep 2025 11:40 GMT
… , reflecting human evolution and genetics.
The Arc of Obesity
Long ago, when … stayed lean despite fat-storing genes.
Obesity was purely a fantasy. Around … obese—an epidemic born from the ancient clash between our thrifty genes …
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Coffee Break: The Next Surgeon General, Gene Therapy, Ozone Hole Closes, Daylight Saving Time, and American Socialism
19 Sep 2025 23:22 GMT
… . Sarepta Therapeutics produces a gene therapy (Elevidys) for Duchenne … produces a micro-dystrophin (gene therapy for full-length dystrophin … efficacy: How much gene does the gene therapy actually deliver? … standard time may reduce obesity and stroke.
A new …
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Pharmacotherapy for Obesity: Recent Updates
19 Sep 2025 09:19 GMT
… the parabrachial nucleus via calcitonin gene-related peptide (CGRP) neurons.44 … ), Neuropeptide Y (NPY), and Calcitonin-Gene Related Peptide (CGRP). These hormones … in severely obese adults: a randomized controlled trial (EQUIP). Obesity. 2012;20 …
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<![CDATA[MD Anderson and Phoenix SENOLYTIX Announce Strategic Cross-Licensing Agreement to Enhance Inducible Switch Technologies for Cell and Gene Therapies]]>
19 Sep 2025 01:15 GMT
… the activity of cell and gene therapies.
“While we have … incorporated into both cell and gene therapies, and Phoenix has utilized … cell populations in aging and obesity-related disorders.
“We are … the adoption of cell and gene therapies.”
In addition to the …
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Collaboration with Kenya’s Turkana Community Uncovers Genes Behind Desert Adaptation
18 Sep 2025 19:26 GMT
… urban lifestyles, the very genes that once safeguarded survival now … altered gene expression patterns associated with higher incidences of hypertension, obesity, … natural selection, evolutionary mismatch, kidney genetics, STC1, arid environment, East Africa …
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You | Sep 18, 2025 | 11 min read Obesity-related risks may depend on genes
18 Sep 2025 14:45 GMT
… why some people with obesity remain relatively healthy while … predict, prevent, and treat obesity and its complications,” Chami added … research also identified eight distinct obesity subtypes, each linked to … wanted to find new genes that affect body fat …