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<![CDATA[Vericiguat Improves HFrEF Regardless of Background Therapy, With Justin Ezekowitz, MD]]>
17 Oct 2025 16:49 GMT
… (HFrEF), exhibited excellent background therapy before initiation, which contributed significantly … stimulator, vericiguat restores impaired nitric oxide signaling in patients with HFrEF … patients already on background therapy, such as angiotensin-converting …
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New combination drug therapy effectively treats chronic wound infections
14 Oct 2025 19:14 GMT
… mouse models, where the combination therapy eradicated infections aggressively.
The resulting … standstill. And toxic intermediates like nitric oxide build up, killing the microbe … , also known as “metabolic adjuvant therapy,” could extend well beyond P …
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Dual-Stage Targeted Oral Drug Loaded Nanostructured Lipid Carriers Enhance the Efficacy of Ulcerative Colitis
17 Oct 2025 15:11 GMT
… and rapamycin for breast cancer therapy. Eur J Pharm Biopharm. 2017 … , Xu SW. The role of nitric oxide and oxidative stress in intestinal …
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Monosodium Iodoacetate Induces Knee Osteoarthritis in Rats in a Dose- and Time-Dependent Manner
17 Oct 2025 08:18 GMT
… promotes the production of nitric oxide (NO) and matrix … analysis of variance; NO, nitric oxide; MMPs, matrix metalloproteinases.
… review 2024: epidemiology and therapy. Osteoarthritis Cartilage. 2024; … chondrocytes: a cell therapy model to ameliorate the …
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Multifunctional HBc Virus-Like Particles Reprogram Immunosuppressive Macrophages and Potentiate CD8+ T Cell Responses for Enhanced Cancer Immunotherapy
16 Oct 2025 18:18 GMT
… upregulation of pathways related to nitric oxide synthase biosynthesis (Figure 7G), … with immune checkpoint inhibitor therapy and chemotherapy in frontline … self-Assembled nanoagonist for synergistic therapy against pancreatic ductal adenocarcinoma. …
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N-Acetylcysteine as a Potential Immunomodulator in Tuberculosis: Evidence of IL-2 Elevation in a Pilot Study
16 Oct 2025 09:44 GMT
… not receive any additional NAC therapy). Pregnant and lactating women … the group receiving NAC therapy experienced a significant increase … and protonated form of nitric oxide (●NO).22,23 Literature … restored during anti-mycobacterial therapy.33 M. tb-specific …
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Nine Jewish geniuses who put WashU and St. Louis on the Nobel map
15 Oct 2025 19:33 GMT
… the door to biotechnology, gene therapy and modern genetic medicine.
Berg … Physiology or Medicine for discovering nitric oxide’s role as a signaling …
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Researchers discover genetic cause of hearing loss and identify possible treatments
15 Oct 2025 15:05 GMT
… have led the way to therapy. That is beginning to change … is vital to synthesize nitric oxide.
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Nitric oxide is a cellular messenger … treat orphan diseases.”
Why Nitric Oxide Matters:
Nitric oxide might sound like a substance …
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First Antidote for Carbon Monoxide Poisoning ‘Cleans’ Blood in Minutes
15 Oct 2025 03:22 GMT
… a new engineered protein-based therapy called RcoM-HBD-CCC, … molecules in the bloodstream like nitric oxide, which is vital for … than hour with pure oxygen therapy and five hours without … including as an oxygen delivery therapy or blood substitute. This could …
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Biogenically Synthesized Nanoparticles as Emerging Therapeutics for Leishmaniasis: A Review of Recent Advances and Potential Promises
14 Oct 2025 14:19 GMT
… who were receiving intravenous pentamidine therapy for Pneumocystis carinii Pneumonia. … Karpiński TM. Nanoparticles for cancer therapy: current progress and challenges. Nanoscale … al. Reactive oxygen species and nitric oxide in cutaneous leishmaniasis. J …