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Investigating the Therapeutic Mechanisms of Honeysuckle (China) in Sepsis Through Network Pharmacology and Experimental Validation
02 Jul 2025 23:21 GMT
… pharmacology is extensively applied in traditional Chinese medicine research to clarify drug … between drugs and diseases. This study employs molecular docking and network pharmacology … /MYD88 pathway, a key mediator of proinflammatory cytokine release in …
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Targeting TREM2 on Lung Immune Cells Offers Promising New Approach to Treat Pulmonary Fibrosis
05 Jul 2025 13:04 GMT
Lung macrophages, a type of white blood cell vital for immune defense, play a crucial role in conditions such as idiopathic pulmonary fibrosis (IPF). There are two main varieties of these cells in the lungs: tissue-resident macrophages, which are present …
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Genetic factors may influence how well exercise buffers against childhood trauma
04 Jul 2025 00:46 GMT
A new study published in the Journal of Psychiatric Research suggests that exercise can help reduce the psychological toll of childhood adversity—but only for some individuals. People who experienced adverse childhood environments were more likely to …
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Peppermint tea boosts memory and attention—but why?
02 Jul 2025 18:49 GMT
A new study published in Human Psychopharmacology: Clinical and Experimental adds to growing evidence that peppermint can improve memory and attention in healthy adults. The findings show that drinking a modest dose of peppermint tea improved several types …
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Facilitator and Barrier to Health Information System Use from Health Professionals Perspective: A Scoping Review
07 Jul 2025 11:54 GMT
… physicians, nurses, midwives, pharmacists. This criterion ensured that … acceptance and use of drug-drug interaction alerts: an … systematically registering adverse drug reactions in electronic … learning motivation as a mediator. Front Psychol. 2020; …
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The Crucial Role of the PPAR Signaling Pathway in the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease: An Analysis of Gene Expression and Macrophage Polarization
07 Jul 2025 11:54 GMT
… The dual effects of these drugs, balancing efficacy and adverse … arise from the complex drug-target dynamics, with off … -derived macrophage infiltration. Acta Pharmacol Sin. 2022;43:2351 … regulator RIP140: an important mediator of the inflammatory response …
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Anthraquinones from Rheum officinale Ameliorate Renal Fibrosis in Acute Kidney Injury and Chronic Kidney Disease
05 Jul 2025 15:51 GMT
… , triterpenoid components and their renoprotective pharmacology. Acta Pharmacol Sin. 2024;46(4 … proteinuria and drug therapy for diabetic kidney disease. Front Pharmacol. 2024;15 … 1-aminopyrene as a novel mediator of progressive chronic kidney disease …
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Determinants of Glycemic Control in Thai Adults with Insulin-Treated Type 2 Diabetes Mellitus: A Cross-Sectional Study
05 Jul 2025 09:42 GMT
… . Sirindhorn. DAoTuTPoHRHPMC. Instruction of Antidiabetic Drug Injection Techniques for Medical Personal … PA. Self-management as a mediator of the relationship between social …
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SEPLINE: Socioeconomic Position in Epidemiological Research—A National Guideline on Danish Registry Data
04 Jul 2025 14:41 GMT
… covering healthcare contacts, diagnoses, therapies, drug prescriptions etc.1 All these … example of smoking as a mediator between socioeconomic position and cancer … confounding for both the exposure-mediator and mediator-outcome relationships are critical …
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Dynapenic Obesity Linked to Cardiometabolic Disease Risk
04 Jul 2025 00:00 GMT
… cholesterol, emerged as another critical mediator. Elevated AIP indicates a lipid … research also opens avenues for pharmacological innovation. Agents capable of modulating …