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Multi-Target Synergy Against Acute Lung Injury: Systems Pharmacology Decoding Dahuang-Huangqin Herb Pair’s Therapeutic Mechanism
17 Jul 2025 18:58 GMT
… role of LTB4R—a key mediator of cellular communication—we conducted … .82,83 As an inflammatory mediator, matrix metalloproteinases (MMPs) contribute … interactions between Scutellaria baicalensis and pharmaceutical drugs: insights from experimental studies, …
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FDA Grants Regenerative Medicine Advanced Therapy Designation to Gene Therapy for Knee OA
18 Jul 2025 18:35 GMT
… signaling” (1). A key mediator in the pathogenesis of OA … the safety, tolerability, and pharmacodynamics of a single intra-articular … U.S. Food and Drug Administration Grants Regenerative Medicine … U.S.-Food-and-Drug-Administration-Grants-Regenerative-Medicine- …
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Protein Kinase C-β Inhibition and Survival Signaling after Simulated Cardioplegic-Ischemia/Reperfusion in Nondiabetic and Diabetic Human Coronary Arterial Endothelial Cells
16 Jul 2025 15:12 GMT
… .14
9.26
Hypoxia + drug
93.72
0.42
0 … in nondiabetic cells.
Another mediator and regulator of nitric oxide … iNOS as an anti-apoptotic mediator in cultured cells.33 … apoptosis. Although many proposed pharmacological treatments either remain untested in …
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Frequent egg consumption linked to lower risk of Alzheimer’s dementia, study finds
12 Jul 2025 20:00 GMT
Older adults who eat eggs more than once a week may be less likely to develop Alzheimer’s dementia, according to a new study published in The Journal of Nutrition. The researchers found that participants who ate eggs weekly had a lower rate of clinical …
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Mayotte: Rebuilding after the cyclone Chido
02 Jul 2025 15:21 GMT
When Cyclone Chido hit Mayotte on December 14, it swept across the archipelago and caused considerable damage, both material and, above all, human, exacerbating an already record-breaking poverty situation. Faced with difficulties accessing …
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Mechanosensitive miRNAs in Cartilage and Subchondral Bone Remodeling: Emerging Targets for Osteoarthritis Therapy
19 Jul 2025 16:11 GMT
… identified as a key mediator through which human umbilical … clinical translation, including efficient drug loading into EVs, achieving … apoptosis and osteoarthritis. Biochem Pharmacol. 2022;206:115343. doi … , Kim JO. Nano drug delivery systems for antisense …
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Cell Death-Related Genesets Activity Improved Clinical Concordance and Intrinsically Associated with Alterations in Ulcerative Colitis: Mucosal Healing at Molecular Depth
19 Jul 2025 11:24 GMT
… -based forecast. Inflamm Allergy Drug Targets. 2010;9(1): … complete endoscopic remission. Aliment Pharmacol Ther. 2020;51(3): … using a schizophyllan-based drug delivery system for inflammatory … factor is a critical mediator of systemic inflammatory response …
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Masquerades of horror: How youths turned sacred festivals into feasts of blood (2)
19 Jul 2025 05:49 GMT
… a vessel of memory, a mediator between the visible and invisible … values, those protections are vanishing.
Drug abuse, cultism, and violent masculinity …
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Judiciary promotes ADR as remedy for Ghana’s court case overload
19 Jul 2025 00:16 GMT
… renders an award, while the mediator facilitates agreement between parties,” she … settlement practices in cases of drug abuse where offenders pay off …
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ALB Singapore Rising Stars 2025
18 Jul 2025 10:20 GMT
… is recognised as an Accredited Mediator (Singapore Mediation Centre) and … secured notable acquittals in capital drug cases after extended proceedings, including … edge technologies across industries, from pharmaceuticals to advanced materials. His ability …