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Renalys Pharma reaches Japan PMDA agreement on phase III trials of sparsentan for FSGS and Alport syndrome
20 Oct 2025 12:34 GMT
… an agreement with the Pharmaceuticals and Medical Devices Agency (PMDA) … two phase III clinical trials of sparsentan in Japan … profile compared with active control irbesartan. In Europe, it … new drug application (sNDA) for Filspari for the treatment of …
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Renalys Pharma Reaches Japan PMDA Agreement on Phase III Clinical Trials of Sparsentan for Focal Segmental Glomerulosclerosis (FSGS) and Alport Syndrome (AS)
17 Oct 2025 06:44 GMT
… an agreement with the Pharmaceuticals and Medical Devices Agency (PMDA) … profile compared with active control irbesartan. In Europe, it … new drug application (sNDA) for FILSPARI® for the treatment of … -on-phase-iii-clinical-trials-of-sparsentan-for-focal …
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FULL LIST: Flagyl, Artemether-Lumefantrine among 101 drugs delisted by NAFDAC
30 Sep 2025 20:15 GMT
… Agency for Food and Drug Administration and Control ( … formulations) and cough treatments to vaccines (such as … injectables (like Norditropin), diabetes medicines (Januvia/Janumet), …
B4-2317
Hydrochlorothiazide + Irbesartan
Sanofi Aventis Nigeria Ltd …
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FDA Approves REMS Modification for Sparsentan in IgA Nephropathy
28 Aug 2025 20:26 GMT
… phase 3 PROTECT clinical trial (NCT03762850)2, a randomized … review with the FDA, with a Prescription Drug User Fee … medicine indicated for FSGS.
“[Sparsentan] is becoming a foundational treatment … safety of sparsentan versus irbesartan in patients with IgA …
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Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
12 Aug 2025 12:14 GMT
… treatment with compound dendrobium iron combined with irbesartan … were provided by Hanhui Pharmaceutical Co., LTD.; Amlodipine … from Chengdu Remifensi Biotechnology Co., LTD.
Chromatographic … herbal remedies and antihypertensive Western medications can …
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Research on TCM Comprehensive Treatment of DKD Based on Pathophysiological Mechanism
16 Jul 2025 09:07 GMT
… publication, number of trials, actual number of … medical treatment, which included oral irbesartan, while the treatment … formulations, thereby improving drug targeting and bioavailability … medicines for DKD treatment and management. Acta Pharmaceutica …
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<![CDATA[Understanding Sparsentan in Pediatric FSGS, With Michelle Rheault, MD]]>
08 Nov 2025 16:25 GMT
… of the phase 3 DUPLEX trial demonstrate that sparsentan (Filspari … in proteinuria compared with irbesartan in pediatric patients with … to 2023.
The parent DUPLEX trial, a 108-week, randomized … kidney endpoint compared with irbesartan, consistent with the renal …
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9 Common Blood Pressure Medications and How They Work
10 Jun 2025 19:02 GMT
… Diuretics
Diuretics (water pills) increase the amount … )
Teveten (eprosartan)
Avapro (irbesartan)
Cozaar (losartan)
Benicar ( … Receptor Agonists
These drugs stimulate alpha-2 … Medications?
The extent of your high blood pressure helps determine which treatment …
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Old Drugs, New Hope: Review Explores Repurposing Medicines for Rare Diseases
10 Jun 2025 09:03 GMT
… new drug development, treatment options remain severely limited.
In conversation with Medical … (ARBs) like losartan and irbesartan—typically prescribed for hypertension—in … governed clinical trials. If international regulatory bodies like the FDA or …
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NICE relents and backs drug for IgAN from CSL Vifor
23 May 2025 12:24 GMT
… be eligible for treatment with the drug, which is … been shown in clinical trials to reduce levels of … treatment, which includes generic angiotensin-2 receptor blockers such as irbesartan … director of medicines evaluation, Helen Knight.
The drug will help …