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FDA Removes Sparsentan (Filspari) Advisory Committee Meeting for FSGS sNDA
10 Sep 2025 12:29 GMT
… US Food and Drug Administration (FDA) has informed the … daily, oral medication the first non-immunosuppressive treatment for preventing … with maximum labeled dose irbesartan across adult and … , respectively, with the treatment effect of sparsentan strengthened …
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FDA Approves REMS Modification for Sparsentan in IgA Nephropathy
28 Aug 2025 20:26 GMT
… phase 3 PROTECT clinical trial (NCT03762850)2, a randomized … review with the FDA, with a Prescription Drug User Fee … medicine indicated for FSGS.
“[Sparsentan] is becoming a foundational treatment … safety of sparsentan versus irbesartan in patients with IgA …
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FDA Approves REMS Label Update for Sparsentan (Filspari) in IgA Nephropathy
27 Aug 2025 21:54 GMT
… Jula Inrig, MD, chief medical officer of Travere Therapeutics, … endpoint for the combined treatment group, demonstrating a greater … consistent across all clinical trials conducted to date … dosed active control, irbesartan, including no drug-induced liver injury …
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Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
12 Aug 2025 12:14 GMT
… treatment with compound dendrobium iron combined with irbesartan … were provided by Hanhui Pharmaceutical Co., LTD.; Amlodipine … from Chengdu Remifensi Biotechnology Co., LTD.
Chromatographic … herbal remedies and antihypertensive Western medications can …
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Research on TCM Comprehensive Treatment of DKD Based on Pathophysiological Mechanism
16 Jul 2025 09:07 GMT
… publication, number of trials, actual number of … medical treatment, which included oral irbesartan, while the treatment … formulations, thereby improving drug targeting and bioavailability … medicines for DKD treatment and management. Acta Pharmaceutica …
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Regulatory tracker: Biogen's postpartum depression treatment Zurzuvae wins approval in Europe
02 Jul 2025 21:48 GMT
… Biotech’s topical gene therapy Vyjuvek received a FDA … beat off-label irbesartan when looking at changes … medication for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), the drug …
As Vertex Pharmaceuticals moves ahead with the launch …
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Panama Government Expands List of Low-Cost Medications with Discounts of up to 95%
13 Jun 2025 15:03 GMT
… pharmaceuticals with significant discounts. There are now 110 pharmacies distributing affordable treatments … medications included in the low-cost access program, adding 80 new drugs … 100 mg, Enalapril 20 mg, Irbesartan 300 mg, Indapamide 1.5 …
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9 Common Blood Pressure Medications and How They Work
10 Jun 2025 19:02 GMT
… Diuretics
Diuretics (water pills) increase the amount … )
Teveten (eprosartan)
Avapro (irbesartan)
Cozaar (losartan)
Benicar ( … Receptor Agonists
These drugs stimulate alpha-2 … Medications?
The extent of your high blood pressure helps determine which treatment …
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Old Drugs, New Hope: Review Explores Repurposing Medicines for Rare Diseases
10 Jun 2025 09:03 GMT
… new drug development, treatment options remain severely limited.
In conversation with Medical … (ARBs) like losartan and irbesartan—typically prescribed for hypertension—in … governed clinical trials. If international regulatory bodies like the FDA or …
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NICE Approves Sparsentan for Kidney Disease Treatment
28 May 2025 15:53 GMT
… effectively than standard treatment. The drug may also better … -controlled, phase 3 trial included patients aged 18 … irbesartan group.
The researchers concluded that treatment with sparsentan vs maximally titrated irbesartan … a retired NHS doctor. A well-known …