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Unraveling the Biology of Interferon-Stimulated Genes: Mechanisms, Functions, and Clinical Implications
07 Jan 2026 20:32 GMT
… model of S. aureus osteomyelitis, interferon beta released by osteoblasts initiates autocrine … prediction of response to neoadjuvant treatment of rectal adenocarcinoma. Oncoimmunology. … mouse model of tuberculosis. Mol Pharmaceut. 2016;13:3247–3255. doi …
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Saphnelo self-administration TULIP-SC trial demonstrates statistically significant and clinically meaningful reduction in systemic lupus erythematosus disease activity
06 Jan 2026 09:47 GMT
… treatment period.1,20
The primary endpoint in the trial … 1 of the type I interferon (IFN) receptor, blocking … role, including Phase III trials in cutaneous lupus erythematosus, … , and commercialisation of prescription medicines in Oncology, Rare Diseases, …
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Effects of Blood Pressure and Antihypertensive Drugs on Rheumatoid Arthritis: A Mendelian Randomization, Network Pharmacology, and Experimental Validation
03 Jan 2026 10:39 GMT
… Traditional Chinese Medicine (Ethics … Shanghai ShangPharma Xinyi Pharmaceutical Co); spironolactone … necrosis factor, interferon-gamma neutralizing … drugs or immunosuppressants) to improve treatment outcomes, and conducting randomized controlled clinical trials …
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The PPE2 protein of Mycobacterium tuberculosis is responsible for the development of hyperglycemia and insulin resistance during tuberculosis
06 Jan 2026 19:26 GMT
… , use of immunosuppressive drugs and diabetes (Ai … analysis revealed that PPE2 treatment could significantly downregulate … expression profiles and elevated interferon-gamma signaling, indicating … Research, at Bhagwan Mahavir Medical Research Centre (BMMRC) …
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Beyond Thresholds: CMV Replication Kinetics as Early Predictors of Clinical Risk in Transplant Recipients
06 Jan 2026 18:14 GMT
… ) is a ubiquitous beta herpes virus. Seropositivity rates … currently available treatments are virostatic. These medications can inactivate … signals regulating type I interferon production: lessons learned … Drug resistance assessed in a Phase 3 clinical trial …
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The Daily Pill Against Cancer, Heart Disease, and Dementia And Scores of Other Diseases
10 Dec 2025 04:21 GMT
… to conventional RA treatments.
10. … drug interactions, and demonstrates an exceptional safety profile in clinical trials … from folk remedy to pharmaceutical-grade nutraceutical. … clinical-trial/9C2F85ACF61EDD0E627494E051237197
83. News-Medical. Preclinical …
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Pliant Therapeutics reports interim PLN-101095 Phase I trial data
05 Dec 2025 13:29 GMT
… showed significant increases in plasma interferon gamma (IFN-γ), ranging from … pharmacokinetic profile.
In the trial, 16 patients with nine … tumours in similar Phase I trials.
“The growing validation … potential to create new treatment options for patients in …
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Multiple Sclerosis Therapeutics Market Growth Accelerates with Biologics & Precision Medicine| DataM Intelligence
02 Dec 2025 12:45 GMT
… Trial Breakthroughs
These therapies are in Phase 3 trials … . This category includes interferon-beta products, S1P receptor … global treatment access. Advancements in precision medicine and … decade. Partnerships between pharmaceutical companies and research …
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Clinicopathological Characteristics of Lichenoid Drug Eruption: A 17-Year Retrospective Study
28 Nov 2025 12:45 GMT
… driven immune response involving interferon-γ (IFN-γ), … remedies, Chinese herbal medications, and traditional herbal pills. Drug causality … causative drugs associated with lichenoid drug eruption.
Treatment … channel blockers and statins. Accurate diagnosis …
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DoP Shortlists Patented, Unlaunched Drugs for Global Tender Exemption, See Full List
26 Nov 2025 21:17 GMT
… Council of Medical Research (ICMR), several central procurement bodies, and pharmaceutical industry … contest the inclusion of any drug by demonstrating local manufacturing capability … + 3 mg
Proprietary
12.
Peg interferon Beta-lA 125mcg/0.5 …