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IMerge Trial
01 Jul 2025 13:20 GMT
… from the IMerge phase 3 trial of imetelstat in lower-risk myelodysplastic … for a sequential, patient-centered treatment approach to enhance quality of …
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Debate: Optimal Initiation of ESAs, Luspatercept, and Imetelstat: Pretransfusion vs Posttransfusion
01 Jul 2025 13:20 GMT
Panelists discuss the debate on optimal timing for initiating therapies in lower-risk myelodysplastic syndromes, balancing early intervention to improve quality of life and prevent complications against a conservative approach favoring treatment initiation …
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Dr Mascarenhas on the Safety of Imetelstat Plus Ruxolitinib in Higher-Risk Myelofibrosis
01 Jul 2025 03:21 GMT
… MD, a professor of medicine at the Icahn School … Tisch Cancer Institute, discussed the safety profile of imetelstat (Rytelo … Importantly, no patients discontinued treatment due to hematologic toxicity, … -term therapy. The trial investigators concluded that the …
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Imetelstat Shows Benefit in RS-Negative, Lower-Risk MDS
01 Jul 2025 02:55 GMT
… phase 2/3 IMerge trial (NCT02598661).1
The data, which … June 2024, the FDA approved imetelstat for the treatment of adult patients with … ;/www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves-imetelstat-low-intermediate …
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Dr Mascarenhas on the Efficacy of Imetelstat Plus Ruxolitinib in Higher-Risk Myelofibrosis
23 Jun 2025 21:09 GMT
… MD, a professor of medicine at the Icahn School … of Excellence for Blood Cancers and Myeloid Disorders, … #47;1b IMproveMF trial (NCT05371964) investigating imetelstat (Rytelo) plus ruxolitinib … explained. The durability of treatment, patient retention on therapy …
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New Drugs, New Decisions: How Pharmacists Are Guiding the Future of Hematologic Care
20 Jun 2025 00:56 GMT
… PharmD, BCOP, from Michigan Medicine in Ann Arbor, Michigan … [MF]—looking at new drugs like imetelstat [Rytelo; Geron Corporation] … advances currently shaping the treatment of hematologic disorders … transformation to secondary cancers or reducing the …
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Dr Komrokji on the Effect of Prior Treatment on Imetelstat Activity in Transfusion-Dependent LR-MDS
18 Jun 2025 20:24 GMT
… the Moffitt Cancer Center; as well as a professor in medicine … sciences in the College of Medicine at the University of South … IMerge trial (NCT02598661) demonstrated that imetelstat retained clinical activity across various prior treatment …
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Updated efficacy of mutant-selective PI3Kα inhibitor RLY-2608 in combination with fulvestrant in patients with PIK3CA-mutant HR+HER2- advanced breast cancer: ReDiscover trial
18 Jun 2025 20:25 GMT
Hematologists Highlight Notable Insights From the 2025 EHA Congress
Post Hoc Analysis Shows Imetelstat Drives Benefit in RS-Negative, Lower-Risk MDS
Bexobrutideg Is Tolerable and Yields High Response Rates in Relapsed/Refractory Waldenström …
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Post Hoc Analysis Shows Imetelstat Drives Benefit in RS-Negative, Lower-Risk MDS
18 Jun 2025 03:15 GMT
… phase 2/3 IMerge trial (NCT02598661).1
The data, which … June 2024, the FDA approved imetelstat for the treatment of adult patients with … ;/www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves-imetelstat-low-intermediate …
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Geron Announces Presentations at ASCO and EHA Underscoring RYTELO® (imetelstat) Efficacy and Safety Across Range of LR-MDS Patients, and Showcasing Momentum of Myelofibrosis Program
28 May 2025 12:46 GMT
… Department, Moffitt Cancer Center. “While imetelstat is already playing … Vice President and Chief Medical Officer of Geron. … commercializing RYTELO (imetelstat) for the treatment of certain patients … ongoing clinical trials, including the IMpactMF trial; (j) …