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<![CDATA[Managing Adverse Events for Patients With MDS Given Imetelstat]]>
14 Oct 2025 00:43 GMT
… , and assistant medical director of the Clinical Trials Office at Yale Cancer Center … notes that although imetelstat is an effective treatment for anemia in transfusion … patient is started on the drug, per the label, they should …
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<![CDATA[Clinical Efficacy and Patient-Reported Outcomes from Phase 3 IMerge Trial]]>
06 Oct 2025 21:04 GMT
… 3 IMerge Trial
The phase 3 IMerge trial evaluated imetelstat, a … levels. These findings highlight imetelstat’s potential as a … the lack of effective treatments for SF3B1-negative disease. … The panelists conclude that imetelstat represents an important new …
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<![CDATA[Dr Mascarenhas on the Role of Imetelstat in the Myelofibrosis Treatment Paradigm ]]>
01 Oct 2025 01:03 GMT
“One application of [imetelstat treatment] is as a bridge … For many patients, this drug could be used outside of … , MD, a professor of medicine at the Icahn School of … Tisch Cancer Institute, discussed the potential role of imetelstat in the treatment …
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<![CDATA[MDS Treatment Advances: Targeted Therapies and Anemia Management]]>
21 Sep 2025 15:21 GMT
… remain standard, while newer drugs like Rytelo (imetelstat) and therapies for IDH1 … comorbidities and medications, which may limit the intensity of treatment or options … conciseness.
For more news on cancer updates, research and education, don …
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JAK Inhibitor Pipeline Outlook 2025: Clinical Trial Studies, EMA, PDMA, FDA Approvals, MOA, ROA, NDA, IND, And Companies
22 Aug 2025 01:56 GMT
… participants treated with imetelstat compared to best … Therapeutics, Pfizer, GSK, Dizal Pharmaceutical, Confluence Life Sciences, Arcutis … , into human clinical trials. SDC-1802 has … drug is in Preclinical stage of its development for the treatment of cancer …
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FibroGen Announces Positive Type C Meeting with the FDA for Roxadustat in Patients with Anemia Associated with Lower-Risk Myelodysplastic Syndromes
07 Aug 2025 11:00 GMT
… Phase 3 trial protocol to the FDA in the … Medicine and Chief of the Division of Hematologic Malignancies at Yale Cancer … agents (ESAs), luspatercept, imetelstat, or lenalidomide in lower- … candidates for the treatment of solid tumors. For more information …
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Dr Mascarenhas on Key Considerations for Clinical Trial Enrollment in Myelofibrosis
30 Jul 2025 03:41 GMT
… , a professor of medicine at the Icahn School … Excellence for Blood Cancers and Myeloid Disorders, … survival prolongation as a treatment goal.
Therapeutic decisions … trial participation.
Mascarenhas also highlighted key considerations for the use of imetelstat …
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IMpact-MF Trial Aims to Show OS Benefit of Imetelstat in Relapsed Myelofibrosis
29 Jul 2025 19:19 GMT
… the Icahn School of Medicine at Mount Sinai and … Leukemia Program at The Tisch Cancer Institute in New York, … 3 trial, and what differentiates imetelstat from currently available treatment options … not great candidates for a drug like this. The cytopenias …
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Quality of Life, Caregiver Impact Key to Future Imetelstat Research in Lower-Risk MDS: María Díez Campelo, MD, PhD
20 Jul 2025 20:40 GMT
… (MDS) Treated With Imetelstat in the IMerge Trial," which she … life findings influence real-world treatment decisions for patients with … patient and also for the doctor to bridge this world.
… patients not responding to the drug. The benefit is clearly …
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Imetelstat Linked to Sustained Health-Related Quality-of-Life Benefits in Lower-Risk MDS: María Díez Campelo, MD, PhD
18 Jul 2025 10:06 GMT
… Myelodysplastic Syndromes Treated With Imetelstat in the IMerge Trial," which she … of patients who responded to treatment.
Watch part 1 to learn … is clearly associated [with] the drug, not with the responding patients …