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Deciphera’s Romvimza secures EC nod for TGCT treatment
18 Sep 2025 10:37 GMT
… pivotal Phase III MOTION trial of vimseltinib, against placebo … previously, except for treatments with imatinib or nilotinib.
The study … Phase I/II trial findings.
According to … member of Ono Pharmaceutical, develops medicines utilising its switch-control …
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Nanocrystalline Drug Delivery Systems for Natural Compounds: Progress, Challenges and Future Opportunities
17 Sep 2025 17:46 GMT
… remedies in the realm of drug development.6
Despite their considerable medicinal … co-loaded with imatinib into the hydrophobic … for the treatment of bronchopulmonary aspergillosis. … polysaccharide nanocrystals as pharmaceutical excipients. Carbohydr Polym. …
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<![CDATA[First-Line TKI Treatment Selection in Newly Diagnosed CML]]>
17 Sep 2025 16:40 GMT
… tyrosine kinase inhibitors (TKIs) like imatinib, nilotinib, dasatinib, and bosutinib. However … of the phase 3 ASC4FIRST trial. These data demonstrated superior molecular … molecular response and considering future treatment-free remission, are central to …
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CYP2C8-Mediated Drug–Drug Interactions and the Factors Influencing the Interaction Magnitude
16 Sep 2025 09:22 GMT
… to comedicate with statins.85
Antidepressants
Fluvoxamine is commonly … adverse events.
Gemfibrozil-Imatinib
Both CYP2C8 and … and clinical pharmaceutical care. Develop new drugs that are … CYP2C8 perpetrators (dose, treatment course, systemic concentrations, …
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AI Tool Identifies Treatments That Reverse Disease States in Cells
10 Sep 2025 21:08 GMT
… that could reshape drug discovery, researchers at Harvard Medical School (HMS) have … treatments such as kinase inhibitors—the authors cite imatinib as an example—drugs … and drug-based experiments, asking the tool to predict various treatment options …
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Liquid Formulations of Oncologic Agents Improves Dosing Consistency, Treatment Adherence in Patients With Dysphagia
04 Sep 2025 13:56 GMT
… of imatinib (Imkeldi), which was FDA approved in 2024 for the treatment of … in collaboration with medical oncologists for toxicity management, drug interactions, and supportive … to] cut a medication and giving them pill splitters to make sure …
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Dr Aldoss on MRD Negativity Outcomes With Ponatinib vs Imatinib in Newly Diagnosed Ph+ ALL
04 Sep 2025 02:02 GMT
… ) negativity outcomes following treatment with ponatinib (Iclusig) or imatinib (Gleevec) in patients … PhALLCON trial (NCT03589326) evaluated the efficacy and safety of ponatinib vs imatinib … vs the imatinib arm, he stated. By the end of treatment, the …
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Emerging Applications of EpCAM-Targeted Nuclear Medicine Probes: Current Research and Future Perspectives
03 Sep 2025 20:34 GMT
… , therapeutic, and biotechnological potential.53 Their … medicine clinical translational pathway, including preclinical studies, clinical trials … trial of imatinib plus binimetinib in patients with treatment … -kinase targeting drugs for patient stratification …
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How to keep cancer drugs affordable after LDC graduation
03 Sep 2025 10:17 GMT
… have kept essential medicines affordable, particularly for … generic cancer drugs. For instance, Beacon Pharmaceuticals produces Tagrix, … patent on the leukaemia drug imatinib, ensuring generics continued. … programmes for cancer treatment are needed to shield …
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Review explores how genetic advances are reshaping SM diagnosis and treatment
03 Sep 2025 03:05 GMT
… transforming diagnosis, prognosis and treatment strategies for systemic mastocytosis (SM … monitor disease progression and treatment response.
Treatment therapies are also increasingly … target KIT p.D816V, while imatinib may benefit patients with alternative …