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<![CDATA[Emerging Use of an Allosteric TKI: Asciminib for the Treatment of Chronic Myeloid Leukemia]]>
18 Oct 2025 00:57 GMT
… ponatinib (Iclusig; Takeda Pharmaceutical Company). Despite the … trials (ACTRN12620000851965).4,13,14
The ASC4FIRST trial … imatinib, bosutinib, dasatinib, or nilotinib). Subjects were stratified by European Treatment … the importance of medication adherence and …
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Computer-Aided Drug Design (CADD) Market Competitive Landscape Report – Towards Healthcare
09 Oct 2025 15:00 GMT
… to design drugs, especially imatinib for cancer. … precision cancer treatments by Australia, … drug toxicity early, and the increasing collaborative ecosystem involving pharmaceutical companies, biotech … Plus, Inc.
Insilico Medicine
Exscientia
Atomwise
Genedata …
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<![CDATA[FDA Issues CRL to NDA for Dasynoc in CML and ALL]]>
08 Oct 2025 19:22 GMT
…
The FDA granted Dasynoc an orphan drug designation in 2022 for the treatment … intolerance to prior therapy including imatinib.
Adults with Philadelphia chromosome-positive …
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CML Survivor Day: ‘For us PGI is a temple, and I have no words to express my appreciation for the doctors here’
28 Sep 2025 18:45 GMT
… Imatinib, popularly known as the ‘magic bullet.’“With regular treatment … the support of the doctors here, and their families … . With regular medication, follow-ups with doctors, support of … generic drugs equivalent in efficacy to branded medicines, and …
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Beyond the Genome: Future of Drugs and Therapeutics in 2050
23 Sep 2025 20:30 GMT
… promising to revolutionize medicine and biotechnology. While it … polypharmacological agents like imatinib that incidentally … in silico trials, adaptive clinical trial designs, … Drug Response Network (DDRN) could revolutionize how we approach medical treatment …
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A Narrative Review of Phase II and III Clinical Trials for the Pharmacological Treatment of Fibrodysplasia Ossificans Progressiva (FOP): Efficacy, Safety, and Challenges in Treatment Strategies
22 Sep 2025 13:16 GMT
… status, brief summary, intervention (medication), primary outcome measures, age … II and III trials of pharmacological treatments for FOP. Palovarotene … , Kaplan FS. Druggable targets, clinical trial design and proposed … on the use of imatinib mesylate in FOP: …
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Deciphera’s Romvimza secures EC nod for TGCT treatment
18 Sep 2025 10:37 GMT
… pivotal Phase III MOTION trial of vimseltinib, against placebo … previously, except for treatments with imatinib or nilotinib.
The study … Phase I/II trial findings.
According to … member of Ono Pharmaceutical, develops medicines utilising its switch-control …
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Nanocrystalline Drug Delivery Systems for Natural Compounds: Progress, Challenges and Future Opportunities
17 Sep 2025 17:46 GMT
… remedies in the realm of drug development.6
Despite their considerable medicinal … co-loaded with imatinib into the hydrophobic … for the treatment of bronchopulmonary aspergillosis. … polysaccharide nanocrystals as pharmaceutical excipients. Carbohydr Polym. …
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<![CDATA[First-Line TKI Treatment Selection in Newly Diagnosed CML]]>
17 Sep 2025 16:40 GMT
… tyrosine kinase inhibitors (TKIs) like imatinib, nilotinib, dasatinib, and bosutinib. However … of the phase 3 ASC4FIRST trial. These data demonstrated superior molecular … molecular response and considering future treatment-free remission, are central to …
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CYP2C8-Mediated Drug–Drug Interactions and the Factors Influencing the Interaction Magnitude
16 Sep 2025 09:22 GMT
… to comedicate with statins.85
Antidepressants
Fluvoxamine is commonly … adverse events.
Gemfibrozil-Imatinib
Both CYP2C8 and … and clinical pharmaceutical care. Develop new drugs that are … CYP2C8 perpetrators (dose, treatment course, systemic concentrations, …