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Bevacizumab plus erlotinib is highly active in HLRCC-associated papillary renal cell carcinoma
05 Sep 2025 20:44 GMT
… trial (NCT01130519)published in the New England Journal of Medicine … multivariable analysis, previous treatment was shown to … The most common treatment-related adverse events ( … trial (NCT04981509) is ongoing to assess the efficacy of bevacizumab and erlotinib …
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Smoking status must be captured in cancer trials, experts say in new study
18 Aug 2025 01:36 GMT
… how the dose of erlotinib has to be doubled … risks confounding trial results, especially if treatment groups are … published evidence, clinical trials still rarely incorporate robust … data, the doctors said, adding that pharmaceutical manufacturers might …
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Prognostic Significance of R-Loops in Lung Adenocarcinoma: Implications for Immune Response and Drug Sensitivity
11 Aug 2025 18:23 GMT
… SuperUltra chemiluminescence reagent (NCM Biotech, P10060).
Statistical Analysis … response to immunotherapy or drug treatments, we performed Tumor … = 2.5e-05), and erlotinib (p = 3.6e-06 … , Nanfang Hospital, Southern Medical University, for their contributions …
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Johnson & Johnson launches The 3rd Opinion in Asia Pacific: a new term to elevate the patient voice in the lung cancer treatment journey
01 Aug 2025 04:44 GMT
… Johnson & Johnson Innovative Medicine Asia Pacific.
Lung cancer … achieve with the first treatment. Treatment options have become … environment where the doctor';s expertise and … A phase II trial of adjuvant erlotinib in patients with resected …
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Rethinking Oncology Trials With a Statistical Methodology That Puts Patients First
28 Jul 2025 19:44 GMT
…
Traditional clinical trials tend to evaluate treatment efficacy through … , the addition of erlotinib to gemcitabine for metastatic … limited adoption by the medical community, despite the … In recent years, the pharmaceutical industry has increasingly adopted …
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New Python Toolkit Automates Single-Cell Lineage Tracing, Accelerates Tumor Drug Resistance Analysis
26 Jul 2025 02:48 GMT
… Dynamics Energises Regenerative Medicine and Cancer Research … pharmaceutical developers, and policymakers better evaluate how cells respond to treatments … inhibitors (osimertinib or erlotinib), this within-clone … outcomes, whereas drug-treated cancer cells …
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Design of combination therapeutics from protein response to drugs in ovarian cancer cells
21 Jul 2025 22:00 GMT
… and Drug Administration (FDA) (e.g., rucaparib, an approved treatment versus … FDA-approved or in late-stage clinical trials.
Potential drug … for inclusion is that statins are reported to have … widely used EGFR inhibitor Erlotinib as the combination partner …
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Integrated Traditional Chinese and Western Medicine in Lung Adenocarcinoma with Rare EGFR Mutation and Nephrotic Syndrome: A Case Report
02 Jul 2025 13:04 GMT
… impacts treatment tolerance due to hypoalbuminemia-induced drug toxicity … complete remission following erlotinib therapy.5 The … analysis from LUX-Lung trials (2/3… and traditional Chinese medicine. The integrated treatment approach achieved remarkable …
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The Evolution of EGFR-Mutated Advanced NSCLC Treatment: Present Considerations and Future Treatment Options
27 Jun 2025 22:08 GMT
… compared with earlier agents like erlotinib and afatinib, and excellent central … through shared decision-making.
Emerging treatment strategies focus on overcoming osimertinib … that maintain brain penetration, antibody drug conjugates with single or bispecific …
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A Systematic Review of SNPs Screening for Platinum-Related Pharmacodynamics and Pharmacokinetics Genes in Non-Small Cell Lung Cancer for Precision Medicine
26 Jun 2025 22:33 GMT
… Medicine
Research and development related to cancer treatment … drugs such as gefitinib, marked a significant milestone. Erlotinib … review and meta-analysis. Pharmaceuticals. 2022;15(4). … Library of Medicine. National Center for Biotechnology Information. Non …