-
Integrated Traditional Chinese and Western Medicine in Lung Adenocarcinoma with Rare EGFR Mutation and Nephrotic Syndrome: A Case Report
02 Jul 2025 13:04 GMT
… impacts treatment tolerance due to hypoalbuminemia-induced drug toxicity … complete remission following erlotinib therapy.5 The … analysis from LUX-Lung trials (2/3… and traditional Chinese medicine. The integrated treatment approach achieved remarkable …
-
The Evolution of EGFR-Mutated Advanced NSCLC Treatment: Present Considerations and Future Treatment Options
27 Jun 2025 22:08 GMT
… compared with earlier agents like erlotinib and afatinib, and excellent central … through shared decision-making.
Emerging treatment strategies focus on overcoming osimertinib … that maintain brain penetration, antibody drug conjugates with single or bispecific …
-
A Systematic Review of SNPs Screening for Platinum-Related Pharmacodynamics and Pharmacokinetics Genes in Non-Small Cell Lung Cancer for Precision Medicine
26 Jun 2025 22:33 GMT
… Medicine
Research and development related to cancer treatment … drugs such as gefitinib, marked a significant milestone. Erlotinib … review and meta-analysis. Pharmaceuticals. 2022;15(4). … Library of Medicine. National Center for Biotechnology Information. Non …
-
Navigating the Treatment Landscape in Non–Clear Cell Renal Cell Carcinoma
23 Jun 2025 14:42 GMT
… features, biologies, and treatment responses. nccRCC histologies include … from RCC clinical trials, which mainly enrolled … investigator-initiated randomized trial, patients with untreated … pembrolizumab and bevacizumab plus erlotinib, are standard options …
-
Bevacizumab and erlotinib combo effective in papillary renal-cell carcinoma patients: NEJM
23 Jun 2025 20:11 GMT
… England Journal of Medicine showed that bevacizumab and erlotinib together demonstrated efficacy … carcinoma have no known therapeutic treatment, and the majority of them … a combination of bevacizumab and erlotinib demonstrated anticancer efficacy in patients …
-
OncLive’s FDA Approval Report: The Regulatory Rundown for May 2025
31 May 2025 02:11 GMT
… This is the first FDA-approved treatment for LGSOC, addressing a … of trials examining avutometinib plus defactinib and excitement antibody-drug … vedotin was paired with erlotinib (Tarceva), it led … letter to Incyte Corporation stating that it could not …
-
Phase 1/2 Trial Investigating ATR-04 for EGFRi-Related Rashes in Lung Cancer
28 May 2025 22:23 GMT
… 1/2 clinical trial of ATR04-484, we … the FDA for ATR04-484 in the treatment of … rash associated with EGFR inhibitors.
Dr. Mary Spellman, chief medical … including drugs like Erbitux (cetuximab), Vectibix (panitumumab), Tarceva (erlotinib) and …
-
NeoGenomics Launches c-MET CDx Assay to Guide Treatment Decisions for Advanced Non-Small Cell Lung Cancer
22 May 2025 11:20 GMT
… U.S. Food and Drug Administration (FDA).*
“Accurate and timely … treatment,” said Dr. Nathan Montgomery, Vice President of Medical … , academic centers, and pharmaceutical firms with innovative diagnostic … Vedotin in Combination With Erlotinib in Patients With …
-
Can Clinical Trials Negate Patentability for Pharma Inventions?
29 Apr 2025 17:24 GMT
… treatment against the standard treatment to secure FDA approval.
Clinical trials … . v. Sunovion Pharmaceuticals, Inc., the … doctors. But, critically, (i) the patients did not know the specific drug … Trial and Appeal Board’s holding of obviousness, stating …
-
Scalp Pustule as a Manifestation of Erlotinib-Induced Skin Toxicity: Report of Two Cases and Literature Review
28 Apr 2025 17:19 GMT
… rash after EGFRI treatment (primarily with cetuximab and erlotinib). Early symptoms were … impact patients’ medication adherence, and high doses of therapeutic drugs may lead … S, et al. Randomized controlled trial on the skin toxicity of …