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<![CDATA[Dr Daver on Persisting Gaps in the Treatment of Relapsed/Refractory Higher-Risk MDS]]>
03 Oct 2025 20:33 GMT
… discussed persisting gaps in the treatment of patients with relapsed… in the phase 3 VERONA trial (NCT04401748), effective standard- … as hydroxyurea, low-dose cytarabine, or supportive care. He … cure. He noted that treatment goals differ between transplant- …
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Kura Oncology and Kyowa Kirin Launch Clinical Trial Evaluating Dual Inhibition of NPM1 and FLT3 Mutations in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML)
01 Oct 2025 11:01 GMT
… inhibitor, combined with cytarabine and daunorubicin (7+ … and deliver novel medicines and treatments with life- … Pharmaceutical Company, Kyowa Kirin has invested in drug discovery and biotechnology … with performing clinical trials, regulatory filings, and …
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Kura Oncology and Kyowa Kirin Announce First Patient Dosed in Pivotal Phase 3 KOMET-017 Trial of Ziftomenib for Frontline Acute Myeloid Leukemia (AML)
29 Sep 2025 20:01 GMT
… of the FDA to allow the trials to use … 3 trial of ziftomenib in combination with standard induction cytarabine … and deliver novel medicines and treatments with life-changing … Pharmaceutical Company, Kyowa Kirin has invested in drug discovery and biotechnology …
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<![CDATA[Oral Agents Provide Greater Acute Myeloid Leukemia Treatment Diversity]]>
25 Sep 2025 23:30 GMT
… , which include stage of treatment, transplant eligibility, and mutational … with a combination of cytarabine or daunorubicin that… more hypomethylating agents.
The treatment of AML depends on … at the beginning of their treatment journey, in consolidation, …
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<![CDATA[Boston’s Best Did Not “Leave the Cannoli” in Battle of Lymphoma Top Trials]]>
25 Sep 2025 16:11 GMT
… MD
The phase 3 TRANSFORM trial (NCT03575351) assessed lisocabtagene … reported results in the treatment-emergent (TE) period. … by all the randomized trials is patients who … (rituximab plus high-dose cytarabine, dexamethasone, and cisplatin alternating …
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<![CDATA[Determining Fitness Is Key in Mantle Cell Lymphoma Treatment Selection]]>
23 Sep 2025 21:53 GMT
… Medicine (Hematology) at Yale University.
Transcript:
The current treatment … changed among most lymphoma doctors. That is based … with rituximab plus dexamethasone, cytarabine, and cisplatin or oxaliplatin … although we have clinical trials ongoing here, so we …
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FDA grants orphan drug designation to ligufalimab for AML
19 Sep 2025 02:12 GMT
… pancreatic cancer.
The FDA has granted orphan drug designation to ligufalimab, a … azacitidine, decitabine or low-dose cytarabine for patients aged 75 years … intensive chemotherapy.
Orphan drug designation is given to treatments for rare diseases …
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Ligufalimab Gains FDA Orphan Drug Status for Acute Myeloid Leukemia
17 Sep 2025 19:48 GMT
… Food and Drug Administration (FDA) for the treatment of acute myeloid … chemotherapy.
Early clinical trials have also shown positive … drugs such as Vidaza, Dacogen (decitabine), or low-dose cytarabine … nor doctors know who is receiving which treatment, helping …
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Actively Recruiting Trials for Lung, Biliary, AML and Small Cell Cancer
16 Sep 2025 02:09 GMT
… clear information about new treatment options. Recent updates include … MAIA Biotechnology.
This phase 2 THIO-101 trial result … company.
The trial is testing Annamycin combined with cytarabine, known … Interactions in Oncology Clinical Trials” by Dr. John Doe …
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Akeso's Ligufalimab (CD47 mAb) Receives FDA Orphan Drug Designation for Acute Myeloid Leukemia (AML)
16 Sep 2025 03:24 GMT
… Drug Designation (ODD) by the U.S. FDA for the treatment … decitabine, or low-dose cytarabine for newly diagnosed AML … fluctuations; the impact of pharmaceutical industry regulation and health … candidates have entered clinical trials (including 15 bispecific…