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Adjuvant Crizotinib Fails to Produce DFS, OS Benefit Over Observation in Resected ALK+ NSCLC
07 Sep 2025 19:11 GMT
… Gerber, MD, of UT Southwestern Medical Center said in a presentation … patients, respectively.
Safety Findings
Treatment with adjuvant crizotinib was associated with notable … , et al. Phase 3 trial of crizotinib vs observation for surgically resected …
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Crizotinib fails to improve disease-free survival in resected early-stage ALK+ NSCLC
07 Sep 2025 13:00 GMT
… #47; UTC +2 ) — Crizotinib, an approved treatment for advanced ALK-positive … ).
The trial, conducted within the ALCHEMIST clinical trials program, … Gerber, MD, a medical oncologist at the UT … .S. Food and Drug Administration approved adjuvant alectinib …
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Crizotinib Does Not Enhance Disease-Free Survival in Resected Early-Stage ALK-Positive NSCLC
07 Sep 2025 11:14 GMT
… S. Food and Drug Administration’s approval … Specifically, patients receiving crizotinib exhibited a median … 4 stroke during treatment. Treatment-related adverse effects … trials aimed at personalized medicine in thoracic oncology.
In summation, the E4512 trial …
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Servier & IDEAYA Biosciences partner to bring darovasertib, a promising uveal melanoma treatment, to patients worldwide
04 Sep 2025 11:55 GMT
… trial evaluating darovasertib in combination with crizotinib … the liver. Current treatment options include radiation therapy … received US FDA (Food and Drug Administration) Breakthrough … an independent international pharmaceutical company governed by …
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Natural Products From Traditional Chinese Medicine: Potential Therapeutic Agents in Cancer Therapy-Induced Cardiotoxicity
02 Sep 2025 16:45 GMT
… progress of modern medicine and biotechnology, the research on … ) inhibitors such as crizotinib and ceritinib, followed … of pharmaceuticals or possible therapeutic targets for CTIC treatment … trials are needed to further explore.
Chemotherapy Targeted Drugs …
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IDEAYA Biosciences To Present First Median Overall Survival Data From Phase 2 Trial Of The Darovasertib / Crizotinib Combination In Metastatic Uveal Melanoma At The 2025 Society For Melanoma Research Congress
29 Aug 2025 20:16 GMT
… IDYA ), a leading precision medicine oncology company, today announced … 01) plus crizotinib as first-line treatment for metastatic … in small-molecule drug discovery, structural biology … conducting preclinical and clinical trials, the regulatory approval …
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5 Medications You Should Avoid Mixing With Ginger Supplement
27 Aug 2025 22:29 GMT
… during treatment with the chemotherapy drug crizotinib may have altered how the medication was … your doctor before combining complementary remedies with prescription treatments.
5. Pain Medications
Some medications used …
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From Patient to Author: Emphasizing Shared Decision Making in NSCLC
19 Sep 2025 02:09 GMT
… a smoker ever, [my doctor] assumed it was pneumonia, … I was originally on Xalkori [crizotinib], which was the only one … Dose adjustments and/or treatment breaks with Lorbrena are great … the negative things about any medication. This was reassuring, even …
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Immunotherapy and T-Cell–Directed Therapy Expand Treatment Approaches in Small Cell Lung Cancer
14 Aug 2025 18:48 GMT
… as the Clinical Research Medical Director at the … personalized treatments, novel targets, and innovative approaches. Antibody-drug … 3 CROWN (NCT03052608) trials advanced the understanding of … generation ALK inhibitor, with crizotinib [Xalkori], an earlier- …
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Uveal Melanoma Treatment Market Set For Major Transformation Through 2034 Fueled By Targeted Therapies And Rising Awareness Delveinsight
30 Jul 2025 00:02 GMT
… PKC inhibitor) and crizotinib (a MET … FDA Type D meeting regarding the Phase 3 trial … treatment market remains highly specialized, with limited but growing competition among pharmaceutical … 8. Treatment Algorithm, Current Treatment, and Medical Practices …