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<![CDATA[From Mutation to Medicine: Targeted Therapies in Lung Cancer]]>
18 Oct 2025 21:25 GMT
… trial (NCT03521154).6-9
Wolf highlights the FLAURA-2 and MARIPOSA trials … (Rozlytrek; Genentech), crizotinib, and epotrectinib (Augtyro … Pharmaceuticals, Inc), which are both FDA approved for treatment … European Society for Medical Oncology 2025 Congress. …
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NICE recommends lung cancer treatment
07 Oct 2025 09:28 GMT
… medicine can now be used as a first-line treatment … as a first-line treatment by the Scottish Medicines Consortium (SMC) … Riely GL. Diagnosis and Treatment of ALK Positive NSCLC. Available … . First-line lorlatinib or crizotinib in advanced alk-positive lung …
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Crizotinib Nanoparticles: Inhalable Lung Cancer Therapy
07 Oct 2025 14:49 GMT
… treatment, researchers have developed an innovative dry powder inhalation formulation containing Crizotinib … collaboration, encompassing pharmaceutical science, nanotechnology, … comprehensive clinical trials to validate … enhanced precision medicine in lung …
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Nanjing Nuoyuan Medical Devices identifies new fluorescent probe
25 Sep 2025 19:27 GMT
Cancer
Nanjing Nuoyuan Medical Devices Co. Ltd. has discovered drug conjugates comprising a … (HGFR; MET) covalently linked to crizotinib through a linker. They are …
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Adjuvant Crizotinib Fails to Produce DFS, OS Benefit Over Observation in Resected ALK+ NSCLC
07 Sep 2025 19:11 GMT
… Gerber, MD, of UT Southwestern Medical Center said in a presentation … patients, respectively.
Safety Findings
Treatment with adjuvant crizotinib was associated with notable … , et al. Phase 3 trial of crizotinib vs observation for surgically resected …
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Crizotinib fails to improve disease-free survival in resected early-stage ALK+ NSCLC
07 Sep 2025 13:00 GMT
… #47; UTC +2 ) — Crizotinib, an approved treatment for advanced ALK-positive … ).
The trial, conducted within the ALCHEMIST clinical trials program, … Gerber, MD, a medical oncologist at the UT … .S. Food and Drug Administration approved adjuvant alectinib …
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Crizotinib Does Not Enhance Disease-Free Survival in Resected Early-Stage ALK-Positive NSCLC
07 Sep 2025 11:14 GMT
… S. Food and Drug Administration’s approval … Specifically, patients receiving crizotinib exhibited a median … 4 stroke during treatment. Treatment-related adverse effects … trials aimed at personalized medicine in thoracic oncology.
In summation, the E4512 trial …
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Servier & IDEAYA Biosciences partner to bring darovasertib, a promising uveal melanoma treatment, to patients worldwide
04 Sep 2025 11:55 GMT
… trial evaluating darovasertib in combination with crizotinib … the liver. Current treatment options include radiation therapy … received US FDA (Food and Drug Administration) Breakthrough … an independent international pharmaceutical company governed by …
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Natural Products From Traditional Chinese Medicine: Potential Therapeutic Agents in Cancer Therapy-Induced Cardiotoxicity
02 Sep 2025 16:45 GMT
… progress of modern medicine and biotechnology, the research on … ) inhibitors such as crizotinib and ceritinib, followed … of pharmaceuticals or possible therapeutic targets for CTIC treatment … trials are needed to further explore.
Chemotherapy Targeted Drugs …
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<![CDATA[Frontline Alectinib Upholds OS Benefit in Advanced ALK+ NSCLC]]>
17 Oct 2025 21:12 GMT
… trial (NCT02075840), which were presented during the European Society for Medical … respectively). For crizotinib, this included … Serono, SFJ Pharmaceutical Ltd., Takeda Pharmaceuticals HK Ltd., … FDA approves Genentech's Alecensa as first adjuvant treatment …