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Clozapine Drug–Drug Interactions and Individualized Dosing in Bipolar Disorder: A Model-Informed Precision Dosing Approach
13 Nov 2025 22:56 GMT
… traditional DDI clinical trials in terms of … and precise medication intervention in complex medication scenarios. … of Variability in Clozapine Exposure. Pharmaceutics. 2021;14( … trial with clozapine?: therapeutic drug monitoring and time to response in treatment …
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Evaluating the Role of Clozapine in Treatment-Resistant Schizophrenia: A Narrative Synthesis of Clinical, Economic, and Quality-of-Life Outcomes
07 Nov 2025 16:14 GMT
… burden of adjunctive medications required to … treatment initiation to prevent repeated hospitalization costs. Trials such as the CLEAR Trial … recent FDA updates to the Clozapine Risk … and adverse drug reaction monitoring during clozapine treatment: consensus …
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<![CDATA[Polypharmacy in Clozapine-Treated Patients: A Retrospective Analysis]]>
18 Nov 2025 03:10 GMT
… medications?
Discussion
Although clozapine is the gold-standard antipsychotic medication for treatment … effects, extrapyramidal symptoms, drug-drug interactions, and mortality.4 … were other antipsychotics (64%), antidepressants (47%), mood stabilizers (31% …
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Investigating of the Experience of Subjective Well-Being of Clozapine Use in Patients with Treatment-Resistant Schizophrenia: A Mixed Method Study
17 Nov 2025 20:41 GMT
… trials of different antipsychotic medications; (3) a treatment … initiating clozapine treatment compared to previous antipsychotic medications. As … research. Ame J Pharmaceut Edu. 2020;84 … G. Randomised controlled trial of clozapine in resistant schizophrenia …
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<![CDATA[Why Therapeutic Drug Monitoring Is Important for Antipsychotics]]>
13 Nov 2025 18:16 GMT
… :
Can you describe what therapeutic drug monitoring means in the context … it’s especially important for clozapine?
How have guidelines and real … evolved in recent years regarding clozapine TDM?
Why do you think …
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What is a black box warning? The label on your medication that you should never ignore
13 Nov 2025 16:30 GMT
… FDA requires pharmaceutical companies to create for each prescription drug … the key clinical trial results that … medications currently carry black box warnings.
Antidepressants are one example. While such drugs … example is clozapine, a drug used to suppress …
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<![CDATA[Innovation in Schizophrenia Treatment: Evenamide Research With Anthony Grace, PhD]]>
12 Nov 2025 01:28 GMT
… drugs cannot do.
PT: How does this medication address unmet needs in schizophrenia treatment … work, since clozapine is usually prescribed to treatment-resistant patients.
This trial should be … .
And in Newron’s clinical trials, there have not been any …
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<![CDATA[Length Matters in Schizophrenia Treatment: Research Shows Benefits of Long-Acting Injectable Treatments ]]>
08 Nov 2025 03:45 GMT
… ’ heel of schizophrenia treatment. Nonadherence rates with … daily pill-taking and ensuring more consistent drug exposure. … outcomes even without clozapine or first-generation antipsychotics … Adherence of Switching Medicaid Beneficiaries With Schizophrenia …
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Drug–Drug Interactions and Individualized Clozapine Therapy in Patients with Depression: Insights from Real-World Data
03 Nov 2025 19:13 GMT
… tht clozapine has an antidepressant effect too.27 Clozapine is … clozapine treatment, (3) therapeutic drug monitoring for clozapine. Patients with depression but missing clinical medical … Sources of Variability in Clozapine Exposure. Pharmaceutics. 2021;14(1 …
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American Association Psychiatric Pharmacists Launches Clozapine Education with Schizophrenia & Psychosis Action Alliance
03 Nov 2025 05:00 GMT
… that address critical topics including clozapine initiation, side effect management, patient … access to this life-saving medication.”
Modules are available at no … the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation …