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Clozapine Drug–Drug Interactions and Individualized Dosing in Bipolar Disorder: A Model-Informed Precision Dosing Approach
13 Nov 2025 22:56 GMT
… traditional DDI clinical trials in terms of … and precise medication intervention in complex medication scenarios. … of Variability in Clozapine Exposure. Pharmaceutics. 2021;14( … trial with clozapine?: therapeutic drug monitoring and time to response in treatment …
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<![CDATA[Why Therapeutic Drug Monitoring Is Important for Antipsychotics]]>
13 Nov 2025 18:16 GMT
… :
Can you describe what therapeutic drug monitoring means in the context … it’s especially important for clozapine?
How have guidelines and real … evolved in recent years regarding clozapine TDM?
Why do you think …
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What is a black box warning? The label on your medication that you should never ignore
13 Nov 2025 16:30 GMT
… FDA requires pharmaceutical companies to create for each prescription drug … the key clinical trial results that … medications currently carry black box warnings.
Antidepressants are one example. While such drugs … example is clozapine, a drug used to suppress …
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<![CDATA[Innovation in Schizophrenia Treatment: Evenamide Research With Anthony Grace, PhD]]>
12 Nov 2025 01:28 GMT
… drugs cannot do.
PT: How does this medication address unmet needs in schizophrenia treatment … work, since clozapine is usually prescribed to treatment-resistant patients.
This trial should be … .
And in Newron’s clinical trials, there have not been any …
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<![CDATA[Iclepertin Found Ineffective in Treating Cognitive Impairment Associated With Schizophrenia]]>
14 Nov 2025 05:21 GMT
… schizophrenia.1 The drug was well … or 2 antipsychotic medications (excluding clozapine). At baseline, … medications in addition to study medication/;placebo, including antidepressants … treatment and placebo groups in individual trials or pooled trial …
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What’s a ‘black box’ warning? A pharmacologist explains how these labels protect patients
13 Nov 2025 13:52 GMT
… medications appear on the product package inserts that the FDA requires pharmaceutical … of the key clinical trial results that showed … menopause.
Antidepressants are one example. While such drugs can …
Another example is clozapine, a drug used to suppress …
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‘There is a gap where Alex should be’: the young woman who lost her life in a neglectful prison system
16 Nov 2025 06:10 GMT
… teens, Alex began self-medicating with cannabis and continued … antipsychotic clozapine, but she was titrated off the drug in … initially coped well without the medication, her mental health rapidly … would not be getting medication for depression and epilepsy …
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My daughter was treated no better than a feral dog - now she is dead
15 Nov 2025 00:05 GMT
… prisoners, with national guidelines stating that prisoners who are at … after being taken off antipsychotic medication before she was arrested … that Alex was not on clozapine after July 2024
an assault … with her needs.
"The treatment by the staff was cruel …
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Excitatory cholecystokinin neurons in CA3 area regulate the navigation learning and neuroplasticity
14 Nov 2025 00:12 GMT
… exploration in training and testing trials (average 1.5 seconds … 47;F between the trial 1 and trial 9 (average 10 … decreased gradually with the CNO treatment while no significant changes … ) received a bilateral microinfusion of Clozapine N-oxide (CNO; 10 …
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Top Chef’s Gail Simmons Talks About Her Brother’s Schizophrenia
13 Nov 2025 19:00 GMT
… president for the Dade County Medical Association, serves on the … challenging to find the right doctors and treatment. “I think about … Saphris), brexpiprazole (Rexulti), cariprazine (Vraylar), clozapine (Clozaril), iloperidone (Fanapt), lumateperone (Caplyta …