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FDA Approves New ADC for Lung Cancer Treatment
15 Aug 2025 14:41 GMT
… datopotamab deruxtecan for people with lung cancers. We have another drug … antibody-drug conjugate) to fight lung cancer, so that's … syndrome in patients that had capecitabine.
One thing, though, is … approval is for EGFR-mutated lung cancers. It doesn' …
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Merck Announces MK-1084, an Investigational KRAS G12C Inhibitor, Shows Antitumor Activity in Phase 1 Trial of Patients With Advanced Colorectal Cancer and Non-Small Cell Lung Cancer Whose Tumors Harbor KRAS G12C Mutations
30 May 2025 12:21 GMT
… ) and non-small cell lung cancer (NSCLC). In patients with … test.
Non-Small Cell Lung Cancer
KEYTRUDA, in combination with … metastatic nonsquamous non-small cell lung cancer (NSCLC), with no … with trastuzumab and CAPOX (capecitabine plus oxaliplatin) or FP …
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Immune and Metabolic Reprogramming Induced by Paclitaxel, Capecitabine and Eribulin in Breast Cancer: Insights into Therapeutic Targets
28 Apr 2025 17:19 GMT
… pharmacologic interventions: eribulin, capecitabine and paclitaxel (Figure … Resistance to Eribulin, Capecitabine and Paclitaxel results … progression on eribulin, capecitabine and paclitaxel, respectively. … with non-small cell lung cancer. Clin Transl Oncol …
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Chemo/Radiation Did Not Yield Increased Pelvic Malignancies in Rectal Cancer
04 Sep 2025 00:12 GMT
… second non-pelvic cancers were lung cancer (24%; n = 35), breast cancer … (FOLFOX; 60%), 5FU (32%), and capecitabine/oxaliplatin (CapeOx; 4%).
Eligible …
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Puma Biotechnology Announces Presentation of Findings from a Phase I/Ib Study of Alisertib in Advanced EGFR-Mutated Lung Cancer
03 Jun 2024 18:48 GMT
… advanced osimertinib-resistant EGFR-mutated lung cancer,” was presented by Turja Chakrabarti … the FDA in combination with capecitabine for the treatment of adult … with extensive-stage small cell lung cancer.
Further information about Puma Biotechnology …
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Bevacizumab by F. Hoffmann-La Roche for Small-Cell Lung Cancer: Likelihood of Approval
17 May 2024 03:08 GMT
… Avastin in combination with xeloda or paclitaxel is indicated … squamous non-small cell lung cancer (with carboplatin and … carcinoma, non-small cell lung cancer, metastatic colorectal cancer, … adjuvant non small cell lung cancer (NSCLC), metastatic liver …
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Two Datopotamab Deruxtecan Applications Validated in the EU for Patients with Advanced Nonsquamous Non-Small Cell Lung Cancer or HR Positive, HER2 Negative Breast Cancer
04 Mar 2024 10:29 GMT
… nonsquamous non-small cell lung cancer (NSCLC) who … -agent chemotherapy (eribulin, capecitabine, vinorelbine or gemcitabine) … Small Cell Lung Cancer
Nearly 500,000 lung cancer cases were … References:
1 Cancer.net. Lung Cancer – Non-Small Cell: Statistics …
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Puma Biotechnology Announces Initiation of ALISCA-Lung1 Phase II Trial of Alisertib in Small Cell Lung Cancer
13 Feb 2024 13:43 GMT
… for alisertib in small cell lung cancer.
“Treatment options for … of alisertib in small cell lung cancer and, more specifically, … FDA in combination with capecitabine for the treatment of … the treatment of small cell lung cancer and breast cancer.
Further …
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Puma Biotechnology Receives FDA Orphan Drug Designation for Alisertib for the Treatment of Small Cell Lung Cancer
21 Sep 2023 20:17 GMT
… of patients with small cell lung cancer (SCLC). SCLC is an … the treatment of small cell lung cancer,” said Alan H. Auerbach, … the FDA in combination with capecitabine for the treatment of … the treatment of small cell lung cancer and breast cancer.
Further …
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Puma Biotechnology Announces FDA Clearance of IND for Alisertib in Small Cell Lung Cancer
08 Aug 2023 12:35 GMT
… extensive stage small cell lung cancer who have progressed after … for alisertib in small cell lung cancer.
“Treatment options for … FDA in combination with capecitabine for the treatment of … the treatment of small cell lung cancer and breast cancer.
Further …
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