… their relevance far beyond weight loss. GLP-1–based … Severity Index (PASI) scores, body mass index (BMI), neutrophil counts, and quality- … 47;overweight, similar to weight-related conditions like hypertension … doses rather than full weight-loss regimens. “A …

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… It includes adults with obesity (BMI≥30.0 kg/m2 … and clinically meaningful placebo-adjusted weight loss of 22.5% ( … efficacy estimand) without reaching a weight loss plateau at 48 weeks … estimand, the placebo-adjusted weight loss achieved with CT-388 …

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