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Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
26 Mar 2024 16:59 GMT
… to note that three compounds (vorinostat, Y-33075, and GSK-1070916 … on the proteome due to drug treatment could reveal new information concerning … -HRP secondary antibody (Santa Cruz Biotechnology, sc-2004).
Cell cycle synchronization …
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New trial hints at a possible HIV cure approach: Wake up latent virus hiding in the body, then kill it" data-before-rewrite-localise="/health/hiv/new-trial-hints-at-a-possible-hiv-cure-approach-wake-up-latent-virus-hiding-in-the-body- …
22 Mar 2024 19:40 GMT
… be wiped out.
The treatment isn't enough … David Margolis, a professor of medicine, microbiology and immunology, and … hiding
With modern antiretroviral drugs, doctors can prevent HIV from … team attempted this with vorinostat, a drug shown to "wake …
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Drug Repurposing Strategies, Challenges and Successes
04 Mar 2024 15:04 GMT
… trial to evaluate repurposed FDA-approved drugs for Rett Syndrome, including vorinostat, … as a treatment for impotence after clinical trials revealed potent … drug prediction integrated with medical record analysis uncovers differential associations of statins …
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Researchers find how anti-cancer drug can improve symptoms after stroke
01 Mar 2024 07:13 GMT
… advantages of vorinostat in animal models following a stroke.
The medication has … from strokes.
This drug, used in the treatment of one type of … correct design of future clinical trials to test its efficacy and …
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Science News | Researchers Find How Anti-cancer Drug Can Improve Symptoms After Stroke
29 Feb 2024 14:00 GMT
… advantages of vorinostat in animal models following a stroke.
The medication has … Grand Wedding.
This drug, used in the treatment of one type of … correct design of future clinical trials to test its efficacy and …
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Anti-cancer drug shows promise in treating brain injuries after stroke
28 Feb 2024 17:57 GMT
… ) were able to demonstrate that vorinostat (suberoylanilide hydroxamic acid) has great … from strokes.
This drug, used in the treatment of one type of … correct design of future clinical trials to test its efficacy and …
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New Trial Shows a Cure for HIV May be Possible
20 Feb 2024 15:20 GMT
The cancer drug Zolinza (vorinostat) along with an … immunotherapy has been shown in a small trial … (UNC) School of Medicine, treated nine patients with … Sarah Kenan Distinguished Professor of Medicine, Microbiology & Immunology, …
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New Trial Highlights Incremental Progress Towards a Cure for HIV-1
13 Feb 2024 15:57 GMT
… lives. However, despite these treatments, some HIV still lingers … destruction.
A new clinical trial led by Cynthia Gay, … of Medicine suggests that a combination of the drug vorinostat and … given multiple doses of vorinostat. Researchers then extracted immune …
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Tumor Purity-Related Genes for Predicting the Prognosis and Drug Sensitivity of DLBCL Patients
01 Feb 2024 23:54 GMT
… prognostic outcomes and treatment sensitivity by detecting … Hospital Chinese Academy of Medical Sciences. Informed consent … clinical practice or clinical trials searched in Pubmed. … Oxaliplatin, Vincristine, Vorinostat, and Bortezomib, but no drug could work …
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Department of Defense Grant to Power Multisite Trial of Rett Syndrome Therapy
17 Jan 2024 19:08 GMT
Vanderbilt University Medical Center (VUMC) has … clinical trial that will evaluate repurposed FDA-approved drugs as treatment … .”
The umbrella trial will compare ketamine, vorinostat, and donepezil … clinical research and coordinating trials that have not only …