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Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats
10 Apr 2024 07:09 GMT
… vildagliptin, saxagliptin, … drugs and three very common structural modification strategies in pharmaceutical … drug design and medicinal chemistry strategies in the fight against diabetes … treatment of diabetic kidney disease. Expert Opin Investig Drugs …
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Revolutionizing Treatment Strategies for Autoimmune and Inflammatory Disorders: The Impact of Dipeptidyl-Peptidase 4 Inhibitors
23 Mar 2024 05:15 GMT
… anti-diabetic medications for the treatment of type 2 diabetes. … Food and Drug Administration’s (FDA) independent advisory … trial, a major multicenter clinical study, compared saxagliptin … remedies are being considered to treat COVID-19 including phage-vaccine …
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Efficacy and Safety of the Utilization of Dipeptidyl Peptidase IV Inhibitors in Diabetic Patients with Chronic Kidney Disease: A Meta-Analysis of Randomized Clinical Trials
23 Mar 2024 10:10 GMT
… is safe for treatment in diabetic patients undergoing HD. … be a misconception that saxagliptin medication is linked to … , according to the pharmaceutical manufacturer that supplied details … week randomized placebo-controlled trial. Diabetes Obesity Metab. 2011 …
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Dapagliflozin Pretreatment Prevents Cardiac Electrophysiological Changes in a Diet and Streptozotocin Induction of Type 2 Diabetes in Rats: A Potential New First-Line?
20 Mar 2024 09:41 GMT
… glycemic control, medical management primarily … by AstraZeneca Pharmaceuticals LP, the … trial in healthy human volunteers showed that empagliflozin treatment … diabetes. further augmentation of the effects with saxagliptin, a DPP4 inhibitor. Cardiovasc Drugs …
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Diabetes Management in the Hospitalized Patient
14 Mar 2024 16:00 GMT
… trials taken together show that insulin treatment … 2 inhibitors, stating that they should … multicentre randomized clinical trial. Diabetes Obes Metab. 2019 … diabetes medicines containing saxagliptin and alogliptin. March 7, 2018. www.fda.gov/drugs/drug …
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2023 First Generic Drug Approvals
08 Mar 2024 22:36 GMT
… Imaging Bulk Package
Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Gadavist ( … Bulk Package
B. Braun Medical, Inc.
Calcium Gluconate in … type 2 diabetes mellitus when treatment with both saxagliptin and metformin … are refractory to other drugs
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213267
Thalidomide …
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Appeals court: Diabetes drug causation claims don’t stand up
15 Feb 2024 00:09 GMT
… plaintiffs claimed that Onglyza (saxagliptin) and Kombiglyze (saxagliptin/metformin hydrochloride), developed … their heart failure.
BioWorld Regulatory Diabetes U.S.
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Appeals court sides with AstraZeneca, BMS, McKesson in saxagliptin heart failure case
14 Feb 2024 20:04 GMT
… a case alleging that diabetes products containing saxagliptin can cause heart …
Saxagliptin is the key ingredient in the discontinued type 2 diabetes treatments Onglyza … in 2016, an FDA safety review found that saxagliptin and another DPP …
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Case Dismissed: Appeals Court Slams Expert Witness in Diabetes Drug Lawsuits
15 Feb 2024 07:56 GMT
… district litigation over the diabetes drug saxagliptin, a case that … expert witnesses, including medical malpractice and product … FDA, which triggered many class-action lawsuits against the drug … court rulings.
The pharmaceutical companies were represented in …
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July - September 2023 | Potential Signals of Serious Risks/New Safety Information Identified by the FDA Adverse Event Reporting System (FAERS)
02 Jan 2024 18:39 GMT
… )
Post-treatment T-cell malignancy
FDA is evaluating … FDA warns of rare but serious drug reaction to the antiseizure medicines … Jardiance (empagliflozin)
Qtern (saxagliptin and dapagliflozin)
Segluromet ( … extended-release)
Diabetic ketoacidosis
The “Warnings …