-
Cancer cell discovery reveals two potential drug targets against skin cancer
18 Apr 2024 13:10 GMT
… environment could offer potential new drug targets to stop skin cancer … to make predictions about which drugs might be successful, by using … can be quite difficult to treat. For a metastatic cell, … to the development of new treatments for metastatic melanoma.”
-
Immunotherapy and Targeted Therapy Regimens for Melanoma
18 Apr 2024 14:49 GMT
… trial, a clinical trial in which patients with metastatic melanoma … #47;STAT, whatever the treatment, always do better. There… FDA-approved drug that functions primarily as a c-MET inhibitor. Those drugs … the only approved drug in uveal melanoma that's …
-
Second-Line Treatment of Pancreatic Adenocarcinoma: Shedding Light on New Opportunities and Key Talking Points from Clinical Trials
18 Apr 2024 07:34 GMT
… trial of an anti-ERBB3 monoclonal antibody used to treat … are the only KRAS targeted treatments FDA approved in cancer. Specifically, … cancer cells. Cancer Chemother Pharmacol. 2006;57(2):165– … patients (pts) with advanced melanoma or a PD-L1+advanced …
-
Majority of Cancer Drugs with Accelerated FDA Approval Did Not Show Clinical Benefit After 5 Years
17 Apr 2024 21:35 GMT
… treatment in HIV patients, it is most commonly used for oncology drugs … clinical benefits of these medications, researchers analyzed 129 … combination with dexamethasone to treat patients with relapsed… For Unresectable, Metastatic Melanoma
References
1. Liu …
-
Nivolumab Plus Talazoparib Does Not Induce Responses in Heavily Pretreated Melanoma
17 Apr 2024 21:19 GMT
… low response rates to treatment: uveal melanoma, blue nevus melanoma, BAP1 mutations, low … in the trial, 3 had cutaneous melanoma, 2 had uveal melanoma, and 2 … LB, et al. Phase II trial of nivolumab in combination with …
-
Safety of Cancer Treatments in Patients With Multiple Sclerosis: Prashanth Rajarajan, MD, PhD
17 Apr 2024 18:07 GMT
WATCH TIME: 6 minutes
"The checkpoint inhibitors seem to be safe from the perspective of not exacerbating the underlying neurologic condition."
Research shows an association between the use of immune checkpoint inhibitors (ICIs) and immune- …
-
Explaining uveal melanoma’s resistance to conventional immunotherapies
17 Apr 2024 18:06 GMT
… tumour microenvironment and successfully treat some patients.”
Originating … . When metastasis occurs, treatment becomes difficult and the … to immune checkpoint inhibitor drugs,” said Dr Kammula. … trial at Pitt for patients with metastatic uveal melanoma. …
-
Checkpoint Inhibitors: A New Hope for Cancer Treatment
17 Apr 2024 17:02 GMT
… of anti-cancer drugs called checkpoint inhibitors, which the FDA approved for … the first time in 2011 for melanoma treatment.
This … realizations. The Bristol-Myers Squibb Pharmaceutical Research Institute revealed in 1992 …
-
TIL Therapy Promising in Uveal Melanoma, Tool Predicts Responders
17 Apr 2024 15:54 GMT
… tumor microenvironment and successfully treat some patients,” Kammula said … Drug Administration earlier this year for the treatment of advanced melanoma. … the optimal time to treat a patient with … therapy in a uveal melanoma trial. He also mentioned that …
-
Derm-Biome Pharmaceuticals’ topical therapy shows positive results in preclinical skin cancer trial: drug prevents the development of precancerous skin conditions and treats existing skin cancers with no observable side effects.
17 Apr 2024 14:15 GMT
… healthcare spending.
Derm-Biome Pharmaceuticals is a Vancouver-based … UV-induced skin cancer trial, mice were exposed to … progression was blocked with drug treatment. We actually noticed an … and precancer/non-melanoma skin cancers that are both …