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Chronic Viral Infections Disrupt B Cells, Degrade Antibody Responses
08 Apr 2024 19:56 GMT
… arose during chronic or acute lymphocytic choriomeningitis virus (LCMV) infection in mice. … cases of chronic viral infection. “… chronic viral infections such as … seq during acute versus chronic lymphocytic choriomeningitis viral infection, we identified a …
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We've learned a lot from lymphocytic choriomeningitis virus--now the time has come to fight it
28 Mar 2023 23:28 GMT
… vaccines or therapies available for lymphocytic choriomeningitis virus (LCMV) infection. This pathogen spreads … for antibody-mediated neutralization of Lymphocytic choriomeningitis virus," include Zeli Zhang, Dawid …
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HOOKIPA Pharma Announces FDA Clearance of its Investigational New Drug Application for HB-500 for the Treatment of Human Immunodeficiency Virus
20 Nov 2023 12:01 GMT
… conducted with a simian immunodeficiency virus (SIV) model, commonly used in … therapeutic vaccination significantly reduced SIV viral load and clinical illness in … . One vector is based on lymphocytic choriomeningitis virus (LCMV) as its arenaviral backbone …
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Low serotonin levels observed in long COVID and other viral infections
20 Oct 2023 10:40 GMT
… proposed theories include unresolved viral reservoirs, chronic inflammation, … acid (RNA) extraction and viral quantification.
Advanced techniques including … acute vesicular stomatitis virus (VSV), chronic lymphocytic choriomeningitis virus (LCMV), and poly …
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HOOKIPA Pharma announces publication of preclinical data of hepatitis B virus (HBV) therapeutic vaccine developed in collaboration with Gilead Sciences
18 Oct 2023 11:01 GMT
… specific to hepatitis B virus with high antibody … It uses the Lymphocytic Choriomeningitis Virus and Pichinde Virus as arenaviral backbones, … highly conserved hepatitis B virus antigens. HOOKIPA’s alternating … Hepatitis B
Hepatitis B virus is the leading cause …
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Immature immune cells near dural sinuses linked to neonatal viral meningoencephalitis
09 Oct 2023 12:09 GMT
… used the lymphocytic choriomeningitis virus (LCMV) model to examine virus propagation within central … venous sinuses contributes to viral meningoencephalitis in neonates. Image … how adaptive immunity controls viral propagation. All through quantification …
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Hookipa Pharma announces pivotal phase 2/3 trial design for HB─200 in combination with pembrolizumab
27 Apr 2024 13:10 GMT
… arenaviral backbones based on lymphocytic choriomeningitis virus (LCMV) and pichinde virus (PICV). Both express …
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HOOKIPA Pharma Announces Pivotal Phase 2/3 Trial Design for HB-200 in Combination with Pembrolizumab
25 Apr 2024 11:01 GMT
… arenaviral backbones based on lymphocytic choriomeningitis virus (LCMV) and pichinde virus (PICV). Both express …
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Might Hepatitis D Virus Cause More Diseases Than Initially Thought?
16 Jun 2023 17:09 GMT
… endogenous virus, murine leukemia virus (MLV), human immunodeficiency virus (HIV), avian influenza virus (AIV), lymphocytic choriomeningitis virus … those of normal hepatitis D virions. Lymphocytic choriomeningitis virus also managed to act as …
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Cell Type Key to Successful Immunotherapies for Chronic Viral Infections Identified
20 Feb 2023 10:39 GMT
… immunotherapeutic treatments to control chronic viral infections. These dendritic cells … target to improve virus control during chronic viral infection.
The study … mouse model of the chronic lymphocytic choriomeningitis virus that partly resembles human …