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Study Finds US Doctors Underprescribe FDA-Approved New Antibiotics
19 Apr 2024 21:04 GMT
… prescribe less-effective generic medicines instead of FDA-approved seven next- … of bacteria resistant to multiple drugs and increasingly resistant to … imipenem-relebactam-cilastatin, and cefiderocol.
The study found that doctors prescribed older medicines …
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ACP issues clinical recommendations for newer diabetes treatments
19 Apr 2024 14:26 GMT
… treatments of adults with Type 2 diabetes
Reviews evidence of newer medications … . Food and Drug Administration (FDA) for 7 … vaborbactam, plazomicin, eravacycline, imipenem–relebactam–cilastatin, and … in pathogen-specific trials, regularly updated guidance …
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Drug Use Evaluation of Tenofovir/Lamivudine/Dolutegravir (TLD) Fixed-Dose Combination for Initiation and Transition Among HIV-Infected Individuals Attending Lumame Primary Hospital, North West Ethiopia
18 Apr 2024 07:34 GMT
… a rise in pretreatment HIV drug resistance, treatment failure, and resource waste … safe and appropriate use of pharmaceuticals, medical procedures, and new research ideas … S, Moradi M. Drug utilization evaluation of imipenem and intravenous ciprofloxacin in …
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Opinion/decision on a Paediatric investigation plan (PIP): Recarbrio, relebactam (MK-7655A),cilastatin sodium,imipenem monohydrate, decision type: PM: decision on the application for modification of an agreed PIP, therapeutic area: Infectious diseases …
05 Apr 2024 15:56 GMT
P/0090/2023 : EMA decision of 10 March 2023 on the acceptance of a modification of an agreed paediatric investigation plan for imipenem (monohydrate) / cilastatin (sodium) / relebactam (MK-7655A) (Recarbrio), (EMEA-001809-PIP01-15- M03)
…
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Contezolid-Containing Regimen Successfully Treated Multiple Drug Resistance Mycobacterium Abscessus Complex Infection of Skin: A Case Report and Literature Review
27 Mar 2024 10:58 GMT
… medication-related adverse effects, and drug-drug interactions, treatment … resistant to minocycline, imipenem, tobramycin and cotrimoxazole. … drug-resistant pulmonary tuberculosis treated with tuberculosis pill … randomized, double-blind trial to evaluate the …
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FDA says yes to Allecra, no to Venatorx UTI drugs
27 Feb 2024 15:25 GMT
… called enmetazobactam, for the treatment of cUTIs in adults, … negative organisms.
Venatorx Pharmaceuticals and partner Melinta Therapeutics … approach with its Recarbrio (imipenem/cilastatin-relebactam) … FDA so that [they] can make this important new medicine …
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Arch Biopartners Has Pre-IND Meeting With FDA to Discuss Repurposing Cilastatin as a New Treatment to Prevent Acute Kidney Injury
27 Feb 2024 12:25 GMT
… capital markets for cilastatin trials. The Company will … imipenem, a β-lactam antibiotic used for the treatment … a wide range of pharmaceutical drugs such as antibiotics ( … hospitalized patients receiving nephrotoxic medications. Endogenous toxins include …
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Model-Informed Precision Dosing of Imipenem in an Obese Adolescent Patient with Augmented Renal Clearance and History of Schizophrenia
27 Feb 2024 08:53 GMT
… events of imipenem,16 he received imipenem treatment at a … nervous system disease, no medical history, use of mechanical … , multicenter trial comparing efficacy and safety of imipenem/ … an important consideration in drug dosing. Pharmaceutics. 2017;9(3): …
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Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
21 Feb 2024 22:47 GMT
… Science Translational Medicine, the Journal of Medicinal Chemistry, and … trials for new antibiotics and 1,300 for anticancer treatments. … controls amikacin and imipenem at eradicating Mab in … aeruginosa, a biofilm-forming drug-resistant bacteria that is …
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Evolution of Peritoneal Dialysis-Associated Peritonitis: Pathogen, Antibiotic Resistance, and the Impact of Lymphocyte Count on Treatment Outcomes
19 Feb 2024 07:39 GMT
… , or ischemia of intraabdominal organs. Medical cure was defined as the … PDAP treated empirically with similar drug regimens. Furthermore, the methods … imipenem/cilastatin monotherapy for treatment of CAPD peritonitis--a randomized controlled trial …