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Why Black St. Louisans with sickle cell disease are leery of the FDA’s new gene therapies
28 Mar 2024 17:42 GMT
… been taking hydroxyurea since 2008. The chemotherapy drug used to … daily sickle cell medication routine and decides to get the treatment, then … which is made by Vertex Pharmaceuticals and CRISPR Therapeutics, is … 32 patients in a trial of the gene therapies, …
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How subpar treatment options allow sickle cell disease to persist | Explained
27 Mar 2024 00:23 GMT
… ’s Essential Medicines List requires the drug to be … Casgevy, developed by Vertex Pharmaceuticals and CRISPR Therapeutics and … develop CRISPR for sickle cell anaemia. Under its Sickle Cell Anaemia Mission, … of hydroxyurea – to those direly in need of treatment.
…
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Vivien Sheehan, MD, PhD, on Choosing the Right Treatment Option for Patients With Sickle Cell Disease
26 Mar 2024 20:20 GMT
… say ‘You must try every FDA-approved therapy for SCD first … molecule drug hydroxyurea has been the main treatment option for patients with sickle cell disease … 2023 with the FDA’s simultaneous approval of Vertex Pharmaceuticals'; and CRISPR …
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Younger Patients With PV May Benefit From Earlier Treatment With Cytoreductive Therapies
27 Mar 2024 19:22 GMT
… Cytoreductive therapies, such as interferons, hydroxyurea, ruxolitinib, and anagrelide, may … treatment durations of 0.5 to 14 years, discontinuation rates for hydroxyurea … in myelofibrosis incidence between treatment with hydroxyurea and phlebotomy only. In …
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Dr. Prithu Sundd Working to Cure Sickle Cell Disease
25 Mar 2024 14:07 GMT
… and Milwaukee Regional Medical Center buildings in … like hydroxyurea and blood transfusions.
I understand that sickle cell … diagnosed with sickle cell disease, what is the treatment process?
… consists of accomplished post-doctoral researchers. Are these …
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Understanding the Etiology and Manifestations of Medication-Triggered Dermatomyositis
26 Mar 2024 23:18 GMT
… The most common medications associated with drug-induced DM were hydroxyurea (50 [30 … .3%]), immune checkpoint inhibitors (27 [16.4%]), statins … guiding management strategies to minimize treatment interruption whenever possible.
Reference: …
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Rusfertide Nearly Eliminates Need for Phlebotomies to Treat Polycythemia Vera
28 Mar 2024 16:59 GMT
… make regular trips to a doctor’s office for the … New England Journal of Medicine are from the first … participants received the drug up front, the VERIFY trial will randomly … existing polycythemia vera treatments—such as the chemotherapy hydroxyurea—are also …
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bluebird bio, Inc. (BLUE) Q4 2023 Earnings Call Transcript
26 Mar 2024 19:10 GMT
… With the FDA approval of LYFGENIA for sickle cell disease last … patients preparing for treatment from multiple treatment centers across … living with sickle cell disease are covered by Medicaid, about … of the other medications. For example, hydroxyurea has to …
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In-Depth Review of Loeffler Endocarditis: What Have We Learned?
28 Mar 2024 06:29 GMT
… mechanisms, staging, diagnosis, treatment and prognosis of Loeffler … most frequently used drugs applied through a … treatment regimen may involve cytotoxic agents such as hydroxyurea, … of standard heart failure medications. Simultaneously, a comprehensive …
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Pegylated Interferons Have Promise but Also Unmet Potential in MPNs
26 Mar 2024 21:53 GMT
… therapeutic option for the treatment of myeloproliferative neoplasms ( … BESREMi; PharmaEssentia). Both medications are recommended as cytoreductive … therapy was given, hydroxyurea was used in almost … of prospective randomized trials with single-agent …